STRUCTURAL STUDIES OF PROTEINS INVOLVED IN PROTEIN TRANSLOCATION

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 我们目前对束流时间感兴趣的项目是双精氨酸蛋白易位复合物的一个组成部分。这是一条原核途径，参与折叠蛋白质跨细胞质膜的易位。这是一个相对较新的途径，如果成功的话，将是该复合物的一个组成部分的第一个结构信息。这也是第一个独立的结构来自我的实验室，我们急于让事情进行下去。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The project that we are currently interested in beam time for is a component of the twin-arginine protein translocation complex. This is a prokaryotic pathway involved in the translocation of folded proteins across the cytoplasmic membrane. This is a relatively new pathway and, if successful, will be the first structural information of a component of the complex. This is also the first independent structure to come from my lab and we are anxious to get things underway.