ULTRA-HIGH FIELD IMAGING AND SPECTROSCOPY OF HUMAN SUBJECTS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 7T Research专门用于磁共振成像和光谱分析的7T全身系统安装在高级成像研究中心。细胞内脂肪的检测、糖原成像和13C核磁共振波谱将是核心3中描述的主要开发目标。然而，该仪器为心脏病学、精神病学和脉搏序列开发开辟了其他领域。几个项目刚刚开始进行：1)由Carol Tamminga博士领导的人脑MR光谱分析，2)人脑的功能磁共振成像，由HZhang Lu博士领导，3)高场与血管支架的相互作用，由Manos Brilakis博士领导，4)2型糖尿病超抵抗患者的细胞内脂肪，由Fred Dunn博士领导，5)充血性心力衰竭患者的细胞内脂肪，由Manisha Shah博士和Sue Beckham博士领导，以及6)用于编辑细胞内脂肪信号的脉冲序列开发，由新教师Choi博士领导。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The 7T research  dedicated 7T whole body system for MR imaging and spectroscopy was installed in the Advanced Imaging Research Center. Detection of intracellular fat, glycogen imaging and 13C NMR spectroscopy will be key development targets as described in Core 3. This instrument, however, opens other areas for investigation in cardiology, psychiatry and pulse sequence development. Several projects are just getting underway: 1) MR spectroscopy of the human brain, lead by Dr. Carol Tamminga, 2) fMRI of the human brain, lead by Dr. Hanzhang Lu, 3) Interactions of high fields with vascular stents, lead by Dr. Manos Brilakis, 4) intracellular fat of ultra-resistant patients with type 2 diabetes, lead by Dr. Fred Dunn, 5) intracellular fat of patients with congestive heart failure, lead by Dr. Manisha Shah and Dr. Sue Beckham, and 6) pulse-sequence development for editing intracellular fat signals, lead by a new faculty recruit, Dr. Changho Choi.