THE ROLE OF LHX2 IN MEDIATING CELLULAR ADHESIVE PROPERTIES

LHX2 在调节细胞粘附特性中的作用

• 批准号: 7724071
• 负责人: EDWIN S MONUKI
• 金额: $ 0.12万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7724071
• 关键词: Adhesives; Biological Assay; Cell Adhesion; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Image; Institution; Mediating; Microscopy; Photons; Property; Research; Research Personnel; Resources; Role; Series; Source; United States National Institutes of Health; mutant; reconstruction; transcription factor

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We examine the transcription factor, Lhx2, and how loss of Lhx2 function effects cell adhesion. Short-term aggregation assays are performed between Lhx2 null mutant and littermate controls. The aggregates are imaged in the LFD by two-channel, 2-photon microscopy in a Z-series. 3D reconstructions of the aggregates will be generated from the Z-series images.

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