Identification of innate receptors for influenza viruses

流感病毒先天受体的鉴定

• 批准号: nhmrc : 509230
• 负责人: Prof Patrick Reading
• 金额: $ 26.55万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identification-innate-receptors-influenza-viruses/99035
• 关键词: Identification; innate; receptors; influenza; viruses

Innate immune mechanisms are vital components of early host defence against pathogens. In this proposal we will define novel components of the innate immune system that first recognize influenza virus as foreign and act to destroy the virus. We will target novel receptors present in lung fluids and on the surface on innate immune cells of the respiratory tract.

先天免疫机制是早期宿主防御病原体的重要组成部分。在这项提案中，我们将定义先天免疫系统的新组成部分，首先识别流感病毒作为外来病毒，并采取行动摧毁病毒。我们将靶向肺液和呼吸道先天免疫细胞表面的新型受体。