BIOSTASTICS CORE

生物统计核心

• 批准号: 7529381
• 负责人: Mark D. Schluchter
• 金额: $ 48.13万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-06 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7529381
• 关键词: Biometry; Biostatistics Core; Cancer Center; Clinic; Clinical; Clinical Research; Clinical Trials; Clinical Trials, Other; Collaborations; Comprehensive Cancer Center; Core Facility; Data; Data Analyses; Data Collection; Databases; Development; Discipline; Education; Ensure; Epidemiology; Funding; Gene Expression; Genetic; Genetic Programming; Human Resources; Individual; Information Management; Ireland; Laboratories; Manuscripts; Measurement; Mission; Monitor; Peer Review; Pilot Projects; Preparation; Protocols documentation; Quality Control; Reporting; Research; Research Design; Research Methodology; Research Personnel; Resource Sharing; Resources; Safety; Statistical Computing; Statistical Methods; Structure; Support of Research; Universities; University Hospitals; anticancer research; base; behavior measurement; cancer genetics; cost; data management; design; member; protocol development; research study; task analysis

The Biostatistics Core Facility is a shared resource to provide statistical and data management support to the Case Comprehensive Cancer Center (Case CCC). The core includes biostatistical and data management staff and consultants from Case Western Reserve University (Case), Ireland Cancer Center at University Hospitals (UH), and the Taussig Cancer Center at the Cleveland Clinic. It brings together individuals with expertise and intellectual resources in 1) biostatistics, 2) clinical trials, 3) epidemiology, 4) statistical computing, and 5) database and information management. The members of this shared resource have a commitment to collaboration with Cancer Center member investigators, applying the discipline of biostatistics to support cancer research and education. The core facility has wide involvement in support of research at the Cancer Center. Activities of this core facility include: 1) design of studies (clinical trials and others) and protocol development; 2) protocol review; 3) data analysis and reporting; 4) manuscript preparation and review; 5) database development and management; 6) trial monitoring; and 7) education for members of the Case CCC in study design, research methods, data collection, and statistical methods for laboratory-based and clinical studies. Specialized analytic support is also available for gene expression studies, and analysis of large databases. The core facility closely supports activities of the Clinical Trials Core Facility in planning studies, collecting and editing data, monitoring trials, and analyzing results. The Biostatistics Core also interacts with the Behavioral Measurement Core Facility to integrate measurement development and analysis tasks, as well as with biostatisticians providing statistical genetics expertise to the Cancer Genetics Program. Coordination of core functions and utilization occurs through regular meetings of key personnel from Case/UH, Ireland Cancer Center, and the Taussig Cancer Center.

生物统计核心设施是一个共享资源，为以下人员提供统计和数据管理支持： 凯斯综合癌症中心（凯斯 CCC）。核心包括生物统计和数据 来自凯斯西储大学 (Case)、爱尔兰癌症中心的管理人员和顾问 大学医院 (UH) 和克利夫兰诊所的陶西格癌症中心。它汇集了 在 1) 生物统计学、2) 临床试验、3) 流行病学、4) 方面拥有专业知识和智力资源的个人 统计计算，5）数据库和信息管理。该共享资源的成员 致力于与癌症中心成员研究人员合作，应用以下学科： 生物统计学支持癌症研究和教育。核心设施广泛参与支持 癌症中心的研究。该核心设施的活动包括：1）研究设计（临床试验和 其他）和协议开发； 2）方案审查； 3）数据分析和报告； 4）手稿 准备和审查； 5）数据库开发与管理； 6）试验监测； 7) 教育 Case CCC 成员在研究设计、研究方法、数据收集和统计方法方面 基于实验室和临床的研究。还可以为基因表达提供专门的分析支持 大型数据库的研究和分析。核心设施密切支持临床试验活动 规划研究、收集和编辑数据、监测试验和分析结果的核心设施。这 生物统计核心还与行为测量核心设施交互以集成测量 开发和分析任务，以及生物统计学家向人们提供统计遗传学专业知识 癌症遗传学计划。通过定期召开会议来协调核心职能和利用 来自 Case/UH、爱尔兰癌症中心和 Taussig 癌症中心的关键人员。