Personal Ozone Monitor

个人臭氧监测仪

• 批准号: 7908299
• 负责人: John W Birks
• 金额: $ 36.49万
• 依托单位: 2B TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7908299
• 关键词: Accident and Emergency department; Admission activity; Adult; Adverse effects; Air; Air Pollution; Asthma; Biological Assay; Biology; Charge; Chemical Interference; Child; Communication; Computer Simulation; Computer software; Computers; Data; Data Collection; Data Display; Databases; Dentistry; Development; Devices; Dimensions; Docking; Electronics; Environmental Exposure; Environmental Health; Environmental Risk Factor; Exposure to; Goals; Graph; Health; Health Sciences; Hospitals; Human; Human Activities; Humidity; Individual; Institutes; International; Internet; Location; Lung diseases; Maps; Marketing; Measurement; Measures; Medicine; Membrane; Memory; Methods; Modeling; Monitor; National Institute of Environmental Health Sciences; New Jersey; Noise; Occupational Health; Ozone; Pattern; Personal Computers; Personal Power; Persons; Phase; Physiological; Printing; Procedures; Research; Resolution; Respiratory physiology; Scientist; Series; Side; Staging; Students; System; Technology; Testing; Time; Travel; Universities; Visit; Wireless Technology; Writing; base; cost; data acquisition; data exchange; design; design and construction; experience; exposed human population; high school; improved; laptop; light weight; liquid crystal; meetings; mortality; ozone exposure; personal log/diary; programs; prototype; public health relevance; tool; toxicant; volunteer

DESCRIPTION (provided by applicant): In this proposal we respond to the call by the National Institute of Environmental Health Sciences (NIEHS) in the PHS 2009-2 Omnibus Solicitation, Exposure Biology Program, Section 1, Technologies for Generating Precise Measures of Environmental Exposures for "new products/devices, tools, assays to improve our ability to precisely measure environmental exposures to individuals with high temporal and spatial resolution." According to the solicitation, the device should be of appropriate scale to be field deployable and/or wearable. Ozone, formed in photochemical air pollution, has well documented adverse effects on human health, including reduction of lung function and aggravation of preexisting respiratory disease such as asthma. Emergency department visits, daily hospital admissions and mortality increase during episodes of high ozone concentration. A Personal Ozone Monitor (POM) is required for environmental health studies of the physiological effects of ozone and for validating computer models of human exposure. In the Phase I project we successfully developed a small (4 x 3 x 1.5 inch), light weight (0.7 lb), low power (2.9 watts), low cost ($795 in parts), battery-operated POM based on the well established method of UV absorbance (an EPA Federal Reference Method). The pocket-sized POM has a precision and accuracy of # 2 ppb, makes new measurements every 10 s and has an internal data logger for downloading data to a personal computer. During the Phase II project proposed here, we will further improve and finalize the development of the POM to include the following: 1) dedicated ground plane on the printed circuit board to further reduce noise, 2) ruggedized, easily manufactured enclosure, 3) human interface consisting of liquid crystal display and keypad, 4) docking station with battery charger, 5) GPS for co-locating measurements with geographical coordinates, and 6) wireless communication between the POM and docking station. Firmware will be developed to support the new functions, and software will be developed for data acquisition and graphing by a computer and for uploading ozone data to the web. The efficacy and accuracy of the POM will be evaluated in personal exposure monitoring studies conducted at the Environmental and Occupational Health Sciences Institute (EOHSI) of the University of Medicine and Dentistry of New Jersey. Several large markets for a pocket-sized ozone monitor have been identified in addition to personal ozone monitoring; these include rapidly growing industrial applications of ozone and the Global Ozone (GO3) Project, an international educational project in which high school students build and operate an ozone monitoring station and share their data as an overlay on the Google Earth" map. PUBLIC HEALTH RELEVANCE: Development of a pocket-sized, battery powered Personal Ozone Monitor (POM) will be completed and evaluated as a means of measuring the time-resolved exposure of individuals during normal daily activities. The POM will facilitate physiological studies of the adverse effects of ozone, formed in air pollution, on human health.

描述(由申请人提供)：在本提案中，我们响应了美国国家环境卫生科学研究所(NIEHS)在PHS 2009-2综合征集，暴露生物学计划，第1部分，生成环境暴露的精确测量的技术部分的呼吁，“新产品/设备，工具，分析，以提高我们以高时间和空间分辨率精确测量个人环境暴露的能力。根据邀请书，该设备应具有适当的规模，以便可现场部署和/或可穿戴。臭氧是由光化学空气污染形成的，它对人类健康的不利影响已有充分证据，包括降低肺功能和加重先前存在的呼吸系统疾病，如哮喘。在臭氧浓度高的时段，急诊科就诊、每日入院人数和死亡率都会增加。个人臭氧监测器(POM)是研究臭氧生理效应的环境健康研究和验证人体暴露的计算机模型所必需的。在第一阶段项目中，我们成功地开发了一款体积小(4 x 3 x 1.5英寸)、重量轻(0.7磅)、低功率(2.9瓦)、低成本(零件价格为795美元)、电池供电的POM，其基础是成熟的紫外线吸收方法(EPA联邦参考方法)。口袋大小的POM的精密度和准确度为#2 ppb，每10个S就进行一次新的测量，并有一个内部数据记录器，可以将数据下载到个人电脑上。在这里提出的第二阶段项目中，我们将进一步改进和完成POM的开发，以包括以下内容：1)印刷电路板上的专用接地板，以进一步降低噪音；2)坚固耐用、易于制造的外壳；3)由液晶显示器和键盘组成的人机界面；4)带电池充电器的扩展底座；5)GPS，用于将测量结果与地理坐标进行协同定位；以及6)POM和扩展底座之间的无线通信。将开发固件以支持新功能，并将开发用于计算机数据采集和绘图以及将臭氧数据上传到网络的软件。POM的有效性和准确性将在新泽西医学和牙科大学环境和职业健康科学研究所(EOHSI)进行的个人暴露监测研究中进行评估。除了个人臭氧监测之外，已经确定了几个袖珍臭氧监测器的大型市场；这些市场包括迅速增长的臭氧工业应用和全球臭氧项目，这是一个国际教育项目，高中生在该项目中建立和运营一个臭氧监测站，并将他们的数据作为谷歌地球地图上的覆盖物共享。 公共卫生相关性：将完成袖珍电池供电个人臭氧监测器(POM)的开发，并对其进行评估，作为一种测量个人在正常日常活动中时间分辨暴露的手段。POM将促进对空气污染中形成的臭氧对人类健康不利影响的生理学研究。