Personal Ozone Monitor

个人臭氧监测仪

• 批准号: 8136179
• 负责人: John W Birks
• 金额: $ 37.13万
• 依托单位: 2B TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2013-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8136179
• 关键词: Accident and Emergency department; Admission activity; Adult; Adverse effects; Air; Air Pollution; Asthma; Biological Assay; Biology; Charge; Chemical Interference; Child; Communication; Computer Simulation; Computer software; Computers; Data; Data Analyses; Data Collection; Data Display; Databases; Dentistry; Development; Devices; Dimensions; Docking; Electronics; Environmental Exposure; Environmental Health; Environmental Risk Factor; Exposure to; Goals; Graph; Health; Health Sciences; Hospitals; Human; Human Activities; Humidity; Individual; Institutes; International; Internet; Location; Lung diseases; Maps; Marketing; Measurement; Measures; Medicine; Membrane; Memory; Methods; Modeling; Monitor; National Institute of Environmental Health Sciences; New Jersey; Noise; Occupational Health; Ozone; Pattern; Personal Computers; Personal Power; Persons; Phase; Physiological; Printing; Procedures; Research; Resolution; Respiratory physiology; Scientist; Series; Side; Staging; Students; System; Technology; Testing; Time; Travel; Universities; Visit; Wireless Technology; Writing; base; cost; data acquisition; data exchange; design; design and construction; experience; exposed human population; high school; improved; laptop; light weight; liquid crystal; meetings; mortality; ozone exposure; personal log/diary; programs; prototype; public health relevance; tool; toxicant; volunteer

DESCRIPTION (provided by applicant): In this proposal we respond to the call by the National Institute of Environmental Health Sciences (NIEHS) in the PHS 2009-2 Omnibus Solicitation, Exposure Biology Program, Section 1, Technologies for Generating Precise Measures of Environmental Exposures for "new products/devices, tools, assays to improve our ability to precisely measure environmental exposures to individuals with high temporal and spatial resolution." According to the solicitation, the device should be of appropriate scale to be field deployable and/or wearable. Ozone, formed in photochemical air pollution, has well documented adverse effects on human health, including reduction of lung function and aggravation of preexisting respiratory disease such as asthma. Emergency department visits, daily hospital admissions and mortality increase during episodes of high ozone concentration. A Personal Ozone Monitor (POM) is required for environmental health studies of the physiological effects of ozone and for validating computer models of human exposure. In the Phase I project we successfully developed a small (4 x 3 x 1.5 inch), light weight (0.7 lb), low power (2.9 watts), low cost ($795 in parts), battery-operated POM based on the well established method of UV absorbance (an EPA Federal Reference Method). The pocket-sized POM has a precision and accuracy of # 2 ppb, makes new measurements every 10 s and has an internal data logger for downloading data to a personal computer. During the Phase II project proposed here, we will further improve and finalize the development of the POM to include the following: 1) dedicated ground plane on the printed circuit board to further reduce noise, 2) ruggedized, easily manufactured enclosure, 3) human interface consisting of liquid crystal display and keypad, 4) docking station with battery charger, 5) GPS for co-locating measurements with geographical coordinates, and 6) wireless communication between the POM and docking station. Firmware will be developed to support the new functions, and software will be developed for data acquisition and graphing by a computer and for uploading ozone data to the web. The efficacy and accuracy of the POM will be evaluated in personal exposure monitoring studies conducted at the Environmental and Occupational Health Sciences Institute (EOHSI) of the University of Medicine and Dentistry of New Jersey. Several large markets for a pocket-sized ozone monitor have been identified in addition to personal ozone monitoring; these include rapidly growing industrial applications of ozone and the Global Ozone (GO3) Project, an international educational project in which high school students build and operate an ozone monitoring station and share their data as an overlay on the Google Earth" map. PUBLIC HEALTH RELEVANCE: Development of a pocket-sized, battery powered Personal Ozone Monitor (POM) will be completed and evaluated as a means of measuring the time-resolved exposure of individuals during normal daily activities. The POM will facilitate physiological studies of the adverse effects of ozone, formed in air pollution, on human health.

描述（由申请人提供）：在本提案中，我们响应美国国家环境健康科学研究所 (NIEHS) 在 PHS 2009-2 综合征集、暴露生物学计划第 1 部分“用于生成环境暴露精确测量的技术”中的号召，以“提高我们以高时间和空间分辨率精确测量个体环境暴露的能力”。根据招标，该设备应具有适当的尺寸，以便可现场部署和/或可穿戴。光化学空气污染中形成的臭氧对人类健康有明显的不利影响，包括降低肺功能和加重哮喘等已有的呼吸道疾病。在臭氧浓度高的情况下，急诊就诊次数、每日住院次数和死亡率都会增加。个人臭氧监测仪 (POM) 用于臭氧生理效应的环境健康研究和验证人体暴露的计算机模型。在第一阶段项目中，我们基于成熟的紫外线吸收方法（EPA 联邦参考方法）成功开发了一种小型（4 x 3 x 1.5 英寸）、轻量（0.7 磅）、低功耗（2.9 瓦）、低成本（零件价格为 795 美元）的电池供电 POM。袖珍 POM 的精度和准确度为 # 2 ppb，每 10 秒进行一次新的测量，并具有一个内部数据记录器，用于将数据下载到个人计算机。在此提出的第二阶段项目中，我们将进一步改进和完成 POM 的开发，包括以下内容：1）印刷电路板上的专用接地层以进一步降低噪声，2）坚固且易于制造的外壳，3）由液晶显示器和键盘组成的人机界面，4）带电池充电器的扩展坞，5）用于与地理坐标进行共定位测量的 GPS，以及 6）POM 之间的无线通信 和扩展坞。将开发固件来支持新功能，并将开发用于计算机数据采集和绘图以及将臭氧数据上传到网络的软件。 POM 的有效性和准确性将在新泽西医学和牙科大学环境与职业健康科学研究所 (EOHSI) 进行的个人暴露监测研究中进行评估。除了个人臭氧监测之外，还确定了袖珍臭氧监测仪的几个大市场；其中包括快速增长的臭氧工业应用和全球臭氧（GO3）项目，这是一个国际教育项目，高中生在其中建造和操作臭氧监测站，并以叠加在“Google Earth”地图上的方式共享他们的数据。 公共健康相关性：将完成袖珍型、电池供电的个人臭氧监测仪（POM）的开发并进行评估，作为测量个人在正常日常活动中时间分辨暴露的一种手段。 POM 将促进空气污染中形成的臭氧对人类健康产生不利影响的生理学研究。