Substance use among adolescent and young adult Hispanic cancer survivors

青少年和年轻西班牙裔癌症幸存者的药物使用情况

• 批准号: 7811048
• 负责人: Joel E Milam
• 金额: $ 8.14万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-29 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7811048
• 关键词: Acculturation; Adolescent; Affect; Age; Alcohol consumption; Alcohol or Other Drugs use; Alcohols; Behavior; Behavioral; California; Cancer Survivor; Caring; Child; Clinical; Cohort Studies; Conflict (Psychology); Data; Development; Diagnosis; Drug usage; Education; Epidemiology; Ethnic group; Family; Funding; Funding Mechanisms; Gender; Goals; Health; Health Promotion; Health behavior; Health education; Hispanics; Hospitals; Income; Institutes; Knowledge; Late Effects; Life; Link; Los Angeles; Malignant Childhood Neoplasm; Malignant Neoplasms; Marijuana; Methods; Morbidity - disease rate; Neuraxis; Not Hispanic or Latino; Parents; Participant; Patients; Pediatric Hospitals; Population; Prevention Research; Psyche structure; Recommendation; Research; Research Personnel; Resources; Risk; Role; Stress; Students; Subgroup; Surveillance Program; Survival Rate; Survivors; Tobacco; Treatment-Related Cancer; Universities; Visit; Work; alcohol behavior; base; behavioral health; case control; childhood cancer survivor; cohesion; cohort; depression; depressive symptoms; design; disorder prevention; experience; follow-up; high school; improved; interdisciplinary collaboration; mortality; prevent; psychosocial; public health relevance; substance use prevention; young adult

DESCRIPTION (provided by applicant): Although treatment advances have increased the survival rates for childhood cancer, most survivors subsequently experience significant early life morbidity and mortality. Thus, childhood cancer survivors (CCS) are recommended to avoidance substance use (alcohol, tobacco, marijuana), to potentially delay or mitigate cancer treatment-related late effects. However, because prior work has been largely based on patients who were diagnosed before 1986, the extent of our knowledge regarding the health behaviors of recently treated CCS is unclear. Further, our understanding of Hispanic cancer survivors is especially limited due to under representation of this ethnic group in research efforts. The purpose of this study is identify risk and protective factors of substance use (alcohol, marijuana, and tobacco) among recently treated Hispanic and non-Hispanic CCS (ages 14-25), including cultural (e.g., acculturation to the U.S), psychosocial (e.g., stress), family (e.g., cohesion and conflict), and demographic (e.g., income, education) factors. To explore the potential impact of the cancer experience on substance use among Hispanics, rates of substance use between Hispanic CCS and age and gender matched non-cancer Hispanic controls (obtained from a separate cohort study of adolescents) will be compared. Results will guide the development of improved health education materials to prevent substance use among CCS, including potential unique approaches for Hispanic CCS. PUBLIC HEALTH RELEVANCE: The extent of our knowledge regarding the health behaviors of recently treated childhood cancer survivors (CCS) is unclear because prior work has been largely based on patients who were diagnosed before 1990. Further, our understanding of health behaviors among Hispanic cancer survivors is especially limited due to underrepresentation of this ethnic group in research efforts. The purpose of this study is to examine the substance use behaviors (alcohol, marijuana, and tobacco) of recently treated Hispanic CCS to provide vital information on appropriate methods to improve these behaviors and ultimately, long term survival of CCS.

描述(由申请人提供)：尽管治疗的进步提高了儿童癌症的存活率，但大多数幸存者随后经历了显著的早期发病率和死亡率。因此，建议儿童癌症幸存者避免使用药物(酒精、烟草、大麻)，以潜在地推迟或减轻癌症治疗相关的后遗症。然而，由于先前的工作主要是基于1986年前确诊的患者，我们对最近治疗的CCS的健康行为的了解程度尚不清楚。此外，我们对拉美裔癌症幸存者的了解尤其有限，因为这一种族在研究工作中的代表性不足。这项研究的目的是确定最近接受治疗的西班牙裔和非西班牙裔CCS(14-25岁)中使用药物(酒精、大麻和烟草)的风险和保护因素，包括文化因素(例如，适应美国的文化)、心理社会因素(例如，压力)、家庭因素(例如，凝聚力和冲突)和人口因素(例如，收入、教育)。为了探索癌症经历对拉美裔美国人物质使用的潜在影响，将比较拉美裔CCS和年龄和性别匹配的非癌症拉美裔对照组(从另一项青少年队列研究中获得)的物质使用率。结果将指导改进的健康教育材料的开发，以防止CCS中使用物质，包括针对西班牙裔CCS的潜在独特方法。 公共卫生相关性：我们对最近接受治疗的儿童癌症幸存者(CCS)的健康行为的了解程度尚不清楚，因为以前的工作主要是基于1990年之前被诊断为癌症的患者。此外，我们对拉美裔癌症幸存者的健康行为的了解尤其有限，因为这一种族在研究工作中的代表性不足。本研究的目的是检查最近治疗的西班牙裔CCS的物质使用行为(酒精、大麻和烟草)，为改善这些行为的适当方法以及最终CCS的长期生存提供重要信息。