Exposure Core

曝光核心

• 批准号: 8045184
• 负责人: S Katharine Hammond
• 金额: $ 10.7万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-07 至 2013-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8045184
• 关键词: Air; Air Pollutants; Air Pollution; Area; Aromatic Polycyclic Hydrocarbons; Birth; California; Carbon; Chemicals; Child; Child health care; Cities; Collaborations; Collection; Communities; Complex; Congenital Abnormality; Data; Data Collection; Data Quality; Elements; Endotoxins; Environment; Epidemiologic Studies; Epidemiologist; Equipment; Evaluation; Event; Funding; Future; Genetic; Health; Human Resources; Inorganic Sulfates; Laboratories; Life; Location; Measurement; Modeling; Monitor; Nitrates; Outcome; Pregnancy Trimesters; Procedures; Process; Protocols documentation; Research; Research Project Grants; Resources; Sampling; Site; Spatial Distribution; Symptoms; Time; Trace metal; Training; Unspecified or Sulfate Ion Sulfates; Wheezing; Work; air contaminant; air monitoring; computerized data processing; cost; design; epidemiology study; experience; falls; improved; innovation; insight; interest; pollutant; quality assurance

The Exposure Assessment Core will be responsible for collecting data to enable estimates of exposures for the three health studies. This will include: 1) collecting and quality checking routine air monitoring data from the Air Resources Board; 2) establishing sampling for polycyclic aromatic hydrocarbons (PAHs) and endotoxin at a central site in Bakersfield and collecting and analyzing samples there for one year to establish the temporal variability for PAHs and endotoxin; 3) collecting contemporaneous samples for PAHs and endotoxin at multiple locations for 1-2 months; 4) exploring the varying spatial pattems for routine air pollutants, PAHs and endotoxin. The data for routinely collected pollutants are needed to understand current exposure gradients in the communities, which will differ by air contaminant, and to facilitate health effects analyses for Project 3. The PM2.5 chemical constituents will include elemental carbon, organic carbon, nitrate, sulfate, and trace metals. In addition, PAH data will be collected at two other air monitoring stations for a 2 month period in fall/winter 2010/201 land endotoxin samples will be collected at 5 other air monitoring stations for a 1 month period in summer 2010. These are being collected to improve the understanding of spatial variability ofthese pollutants in the greater Bakersfield area which is critical to the design of the center. No spatial data of this type currently exist for this area. These exposure data will be used by the health studies as part of their planned work for the pre-center, but will also guide us in planning the data the center will need t o collect when it is a full center.

暴露评估核心将负责收集数据，以便能够估计 三项健康研究。这将包括：1）收集和质量检查例行空气监测数据， 空气资源委员会; 2）建立多环芳烃（PAH）采样， 在贝克斯菲尔德的一个中心地点进行内毒素检测，并在那里收集和分析样本一年，以确定 多环芳烃和内毒素的时间变化; 3）收集同期样品的多环芳烃和 内毒素在多个位置1-2个月; 4）探索常规空气的不同空间模式 多环芳烃和内毒素。需要常规收集的污染物数据来了解 社区目前的暴露梯度，这将因空气污染物而异，并促进健康 项目3的效果分析。PM2.5的化学成分将包括元素碳、有机物、 碳硝酸盐硫酸盐和微量金属此外，我们亦会在另外两个空气监测站收集多环芳烃的数据， 在2010/2021年秋季/冬季的2个月期间，将在其他5个空气监测站收集陆地内毒素样本。 在2010年夏季的一个月期间，监测站。收集这些数据是为了改善 了解这些污染物在大贝克斯菲尔德地区的空间变异性，这对 中心的设计。该地区目前不存在此类空间数据。这些暴露数据将 作为他们为预备中心计划的工作的一部分，但也将指导我们规划 当它是一个完整的中心时，该中心将需要收集的数据。