Exposure Core

曝光核心

• 批准号: 8374737
• 负责人: S Katharine Hammond
• 金额: $ 6.38万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8374737
• 关键词: Air; Air Pollutants; Air Pollution; Area; Aromatic Polycyclic Hydrocarbons; Birth; Carbon; Chemicals; Child; Childhood Asthma; Cities; Collection; Communities; Congenital Abnormality; Data; Endotoxins; Environment; Environmental Health; Epidemiologist; Event; Face; Funding; Future; Genetic; Health; Human Resources; Inorganic Sulfates; Life; Location; Measurement; Modeling; Monitor; Nitrates; Outcome; Pattern; Research; Resources; Sampling; Site; Trace metal; Unspecified or Sulfate Ion Sulfates; Work; air contaminant; air monitoring; computerized data processing; design; experience; falls; improved; innovation; insight; pollutant

The Exposure Assessment Core will be responsible for collecting data to enable estimates of exposures for the three health studies. This will include: 1) collecting and quality checking routine air monitoring data from the Air Resources Board; 2) establishing sampling for polycyclic aromatic hydrocarbons (PAHs) and endotoxin at a central site in Bakersfield and collecting and analyzing samples there for one year to establish the temporal variability for PAHs and endotoxin; 3) collecting contemporaneous samples for PAHs and endotoxin at multiple locations for 1-2 months; 4) exploring the varying spatial patterns for routine air pollutants, PAHs and endotoxin. The data for routinely collected pollutants are needed to understand current exposure gradients in the communities, which will differ by air contaminant, and to facilitate health effects analyses for Project 3. The PM2.5 chemical constituents will include elemental carbon, organic carbon, nitrate, sulfate, and trace metals. In addition, PAH data will be collected at two other air monitoring stations for a 2 month period in fall/winter 2010/201 land endotoxin samples will be collected at 5 other air monitoring stations for a 1 month period in summer 2010. These are being collected to improve the understanding of spatial variability of these pollutants in the greater Bakersfield area which is critical to the design of the center. No spatial data of this type currently exist for this area. These exposure data will be used by the health studies as part of their planned work for the pre-center, but will also guide us in planning the data the center will need to collect when it is a full center.

暴露评估核心将负责收集数据，以便为三项健康研究估计暴露情况。这将包括： 1) 从空气资源委员会收集日常空气监测数据并进行质量检查； 2) 在贝克斯菲尔德中心地点建立多环芳烃 (PAH) 和内毒素采样，并在那里收集和分析样品一年，以确定多环芳烃和内毒素的时间变异性； 3) 多地点同时采集多环芳烃和内毒素样本，历时1-2个月； 4) 探索常规空气污染物、多环芳烃和内毒素的不同空间模式。需要常规收集污染物的数据来了解社区当前的暴露梯度（因空气污染物而异），并促进项目 3 的健康影响分析。PM2.5 化学成分将包括元素碳、有机碳、硝酸盐、硫酸盐和微量金属。此外，将于 2010/201 年秋冬在另外两个空气监测站采集为期 2 个月的多环芳烃数据，将于 2010 年夏季在另外 5 个空气监测站采集为期 1 个月的陆地内毒素样本。收集这些样本的目的是为了加深对大贝克斯菲尔德地区这些污染物的空间变异性的了解，这对于该中心的设计至关重要。该区域当前不存在此类空间数据。这些暴露数据将被健康研究用作中心前计划工作的一部分，但也将指导我们规划中心在成为一个完整中心后需要收集的数据。