Berkeley/Stanford Children's Environmental Health Center

伯克利/斯坦福儿童环境健康中心

• 批准号: 8215621
• 负责人: S Katharine Hammond
• 金额: $ 27.35万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-07 至 2014-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8215621
• 关键词: Administrative Personnel; Air Pollutants; Air Pollution; Area; Asthma; Birth; California; Charge; Child; Childhood; Chronic Disease; Congenital Abnormality; Critiques; Developmental Process; Disease; Documentation; Elements; Environment; Environmental Health; Epidemiologic Studies; Exposure to; Faculty; Goals; Grant; Health; Human Resources; Institutional Review Boards; Life; Low Birth Weight Infant; Monitor; Outcome; Personnel Management; Postdoctoral Fellow; Property; Regulatory T-Lymphocyte; Reporting; Research; Science; Small for Gestational Age Infant; Toxic Environmental Substances; Training; Travel; Work; Writing; early childhood; fetal; graduate student; in utero; medical schools; meetings; member; pesticide exposure; public health relevance; response

Description (provided by applicant): Our Administrative Core (AC) will provide grants management in the following areas: 1) fiscal management; 2) personnel management for the UC, Berkeley personnel; 3) purchasing and property management; 4) coordination with administrative personnel at Stanford School of Medicine; 5) travel and reimbursement; 6) compliance with IRB requirements and renewals; and 7) meeting coordination and minutes recording. The AC also consists of our planned 5-member Advisory Board (AB), whose areas of expertise are outlined in the proposal. Three meetings are anticipated with the AB: 1) at 6 months to provide critique on the Pre-Center startup; 2) at 18 months to review Pre-Center progress and ideas and plans for a full-center application; and 3) at 30 months to evaluate Pre-Center accomplishments and critique of scientific and logistical issues in anticipation of a full-center application. All meetings with the AB will be documented by written notes. The AC also will provide scientific oversight and tracking of progress through monthly meetings of the entire research team, semi-annual retreats, documentation by minutes with action items to monitor progress. Oversight of the training and progress of junior faculty and graduate students and post-doctoral fellows also will be a function of the AC. Details of the plans for oversight and tracking of progress are provided in the AC write up. The AC also will have responsibility to provide timely responses to the funders in terms of submission of reports and ad hoc requests for information or informal meetings. Public Health Relevance: This Core is a required element for the application. Its function is highly relevant, since it is charged with management of all financial, personnel and logistical matters for the Pre-Center. It contains the Pre-Center's plans for the Advisory Board. Our plan for this Core shows clearly that our application represents a fully integrated Pre-Center in terms of science and administration.

描述(由申请人提供)：我们的行政核心(AC)将在以下方面提供赠款管理：1)财务管理；2)加州大学伯克利分校人员的人事管理；3)采购和物业管理；4)与斯坦福医学院的行政人员协调；5)差旅和报销；6)遵守IRB要求和续签；7)会议协调和会议记录。咨询委员会还包括计划中的5人咨询委员会(AB)，其专业领域已在建议中概述。预计将与AB举行三次会议：1)在6个月时对Pre-Center启动提出批评；2)在18个月时审查Pre-Center的进展以及全中心申请的想法和计划；以及3)在30个月时评估Pre-Center的成就以及对全中心申请的科学和后勤问题的批评。所有与AB的会议都将以书面记录在案。 咨询委员会还将通过整个研究团队的月度会议、半年一次的务虚会、以会议纪要形式记录和监测进展的行动项目，提供对进展的科学监督和跟踪。监督初级教师、研究生和博士后研究员的培训和进展也将是咨询委员会的一项职能。监督和跟踪进展的计划的细节载于咨询委员会的书面报告。 咨询委员会还将有责任在提交报告和特别要求提供资料或举行非正式会议方面及时向资助者作出答复。 公共卫生相关性：此核心是应用程序的必需元素。它的职能非常重要，因为它负责管理预科中心的所有财务、人事和后勤事项。它包含Pre-Center为咨询委员会制定的计划。我们对这一核心的计划清楚地表明，我们的应用程序在科学和管理方面代表了一个完全集成的Pre-Center。

项目成果

Spatial and Temporal Distribution of Polycyclic Aromatic Hydrocarbons and Elemental Carbon in Bakersfield, California.

加利福尼亚州贝克斯菲尔德的多环芳烃和元素碳的空间和时间分布。

• DOI: 10.1007/s11869-016-0399-y
• 发表时间: 2016-12
• 期刊: Air quality, atmosphere, & health
• 作者: Noth EM;Lurmann F;Northcross A;Perrino C;Vaughn D;Hammond SK
• 通讯作者: Hammond SK

Secondhand smoke in combination with ambient air pollution exposure is associated with increasedx CpG methylation and decreased expression of IFN-γ in T effector cells and Foxp3 in T regulatory cells in children.

• DOI: 10.1186/1868-7083-4-17
• 发表时间: 2012-09-25
• 期刊: Clinical epigenetics
• 影响因子: 5.7
• 作者: Kohli A;Garcia MA;Miller RL;Maher C;Humblet O;Hammond SK;Nadeau K
• 通讯作者: Nadeau K

Exposure to airborne polycyclic aromatic hydrocarbons during pregnancy and risk of preterm birth.

在怀孕期间暴露于空气中的多环芳烃和早产风险。

• DOI: 10.1016/j.envres.2014.09.014
• 发表时间: 2014-11
• 期刊: ENVIRONMENTAL RESEARCH
• 影响因子: 8.3
• 作者: Padula, Amy M.;Noth, Elizabeth M.;Hammond, S. Katharine;Lurmann, Fred W.;Yang, Wei;Tager, Ira B.;Shaw, Gary M.
• 通讯作者: Shaw, Gary M.

Mapping and modeling airborne urban phenanthrene distribution using vegetation biomonitoring.

• DOI: 10.1016/j.atmosenv.2013.05.056
• 发表时间: 2013-10
• 期刊: Atmospheric environment
• 影响因子: 5
• 作者: E. Noth;S. Hammond;G. Biging;I. Tager

Epigenetically mediated pathogenic effects of phenanthrene on regulatory T cells.

• DOI: 10.1155/2013/967029
• 发表时间: 2013
• 期刊: Journal of toxicology
• 影响因子: 2.9
• 作者: Liu J;Zhang L;Winterroth LC;Garcia M;Weiman S;Wong JW;Sunwoo JB;Nadeau KC
• 通讯作者: Nadeau KC