The functional organization of directionally biassed feedback influences from MT to V1 and the LGN

方向性反馈影响从 MT 到 V1 和 LGN 的功能组织

• 批准号: G0701535/1
• 负责人: Adam Sillito
• 金额: $ 191.13万
• 依托单位: University College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2008
• 资助国家: 英国
• 起止时间: 2008 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G0701535%2F1
• 关键词: functional; organization; directionally; biassed; feedback

In the brain the pathways transferring sensory information from the sense organs, such as the eyes, to higher centers are matched by feedback pathways that run in the opposite direction. Thus the input from the eyes is relayed via a structure called the visual thalamus to the visual cortex, but the visual cortex sends feedback connections back down to the visual thalamus. Indeed numerically these exceed those arising from the eyes. Why does this happen? What do these connections do? They seem to bring the knowledge from the processing at higher levels in the brain back to earlier levels and in some way use this to enhance our ability to perceive the world around us. Here we are probing the role of the higher cortical area concerned with processing motion in the visual world and the way this area is linked into a functional circuit with the primary visual cortex and thalamus. The suggestion is that the feed forward and feedback connections linking three levels in the visual system operate as an integrated whole rather than as separate steps in a sequence.

在大脑中，将感觉信息从感觉器官（如眼睛）传递到高级中枢的通路与反向运行的反馈通路相匹配。因此，来自眼睛的输入通过一个叫做视觉丘脑的结构传递到视觉皮层，但视觉皮层将反馈连接发送回视觉丘脑。在数量上，这些确实超过了那些从眼睛中产生的。为什么会发生这种情况？这些连接是做什么的？它们似乎将大脑中更高层次的知识处理带回到更早的层次，并以某种方式利用这一点来增强我们感知周围世界的能力。在这里，我们要探讨的是与处理视觉世界中的运动有关的高级皮层区域的作用，以及这个区域与初级视觉皮层和丘脑连接成一个功能回路的方式。我们的建议是，前馈和反馈连接连接在视觉系统的三个层次作为一个整体，而不是作为一个单独的步骤在一个序列。