Oregon Comparative Effectiveness Research K12 Program

描述(由申请人提供)：每年投入在研究上的数百亿美元由于可纠正的研究缺陷而被无效地花费。比较有效性审查始终注意到许多研究的代表性和质量方面的问题。这项建议利用OHSU在比较有效性、证据审查、初步研究、利益相关者参与和K项目成功方面的专业知识来培训比较有效性研究(CER)的未来领导者。俄勒冈州比较有效性研究KL2培训计划旨在开展以下方面的研究：1)培训临床和健康服务CER研究人员和领导者进行学术、政府和其他方面的循证、以患者为中心的务实研究；2)教育所有以证据为基础、以患者为中心的真实世界研究领域的学者，从小型描述性研究到大型前瞻性治疗结果评估；以及3)准备研究人员利用尖端的比较有效性技能设计和实施利益相关者参与的、务实的和跨学科的研究项目。俄勒冈州CER培训计划将招收四名博士后学者，每人学习3年。学习体验将包括三个核心要素：1)比较有效性研究中的说教教育；2)基础广泛的经验轮换；3)重要的、有指导的研究体验。所有学者都将参加一个比较效果审查和一个CER项目。该计划的轮换和实地站点包括俄勒冈州循证实践中心、科学资源中心、比较有效性中心、俄勒冈州CareOregon(俄勒冈州医疗补助患者健康计划)、社区健康信息网(安全网诊所网络管理)和AHRQ资助的俄勒冈州农村实践研究网络。 公共卫生相关性：比较有效性(CE)审查始终发现，少数研究提供了有意义的信息，为现实世界的卫生保健提供信息，这表明研究可能更具成本效益。俄勒冈州CER K12项目将利用俄勒冈州EPC、CTSA的资源和成功，以及OHSU在K12项目上的持续成功，培养未来的CER领导者。

DESCRIPTION (provided by applicant): Tens of billions of dollars invested in research are spent ineffectively each year because of correctable research flaws. Comparative effectiveness reviews consistently note problems in the representativeness and quality of many studies. This proposal leverages OHSU's expertise in comparative effectiveness, evidence reviews, primary research, stakeholder engagement, and K program success to train future leaders in comparative effectiveness research (CER). The Oregon Comparative Effectiveness Research K l2 Training Program aims to conduct evidence-based, patient-centered, pragmatic, research that 1) train clinical and health services CER researchers and leaders for academic, governmental, and other settings; 2) educate scholars in all the disciplines of evidence-based, patient-centered, real-world research, from small, descriptive studies to large prospective outcome evaluations of treatment; and 3) prepare researchers to design and implement stakeholder- engaged, pragmatic, and interdisciplinary research projects employing cutting-edge comparative effectiveness skills. The Oregon CER Training Program will enroll four post-doctoral Scholars, each for 3 years of study. The learning experience will feature three core elements: 1) didactic education in comparative effectiveness research; 2) broad-based experiential rotations; and 3) a significant, mentored research experience. All scholars will participate in a comparative effectiveness review and a CER project. Rotation and field sites for this program include the Oregon Evidence-based Practice Center; the Scientific Resource Center; the Comparative Effectiveness Center; CareOregon (Oregon Health Plan for Medicaid patients); the Community Health Information Network (safety net clinic network administration); and the AHRQ-funded Oregon Rural Practice-based Research Network. PUBLIC HEALTH RELEVANCE: Comparative Effectiveness (CE) reviews consistently find that a minority of studies provide meaningful information to inform real-world health care, suggesting that research could be more cost-effective. The Oregon CER K12 Program will leverage the resources and success of Oregon EPC, CTSA, and OHSU's ongoing success with K12 programs to train future leaders in CER.