(COMIX) Coupling biofilm diversity and ecosystem functioning: The role of communication and mixing in microbial landscapes.

（COMIX）生物膜多样性与生态系统功能的耦合：微生物景观中交流和混合的作用。

• 批准号: NE/D522211/1
• 负责人: William Sloan
• 金额: $ 19.14万
• 依托单位: University of Glasgow
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2006
• 资助国家: 英国
• 起止时间: 2006 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=NE%2FD522211%2F1
• 关键词: COMIX; Coupling; biofilm; diversity; ecosystem

While the biodiversity ecosystem functioning (BEF) debate has considerably advanced macroorganismic and theoretical ecology, a central question remains whether (and how) the BEF coupling applies to the microbial world. This is of immense ecological and societal relevance because of the central role of micro organisms in natural and engineered ecosystems. This proposal aims at studying the relationship between biofilm biodiversity and its large-scale ecosystem consequences. Biofilms are matrix-enclosed communities that represent the dominant form of microbial life in most aqueous ecosystems, yet their understanding significantly lags behind their planktonic counterparts. We will place biofilm research in an explicitly spatial context by recruiting conceptual knowledge from landscape ecology. Dialoguing between modelling and experiments, this will allow us to develop a multi-scale computational model that can quantify the interplay between biofilm invasibility and diversity, hydrodynamic mixing and quorum sensing over a range of different spatial scales. We will start at small spatial scales (<0.01 m) and with the simplest assumption that completely random community assembly from a homogeneous source community is unaffected by mixing and communication. We will then systematically move up in scale (> 1000 m) by successively adding complexity from biofilm surface topography, dispersal, hydrodynamics and quorum sensing, and by comparing model predictions with the experimental observations. Ultimately, we will link nitrifier biodiversity in streams to nitrogen cycling and export to larger downstream ecosystems. COMIX will significantly contribute to bridge the conceptual gap that has developed between microbiology and ecology, advance mathematical modelling in microbial ecology across scales, and will be a unique opportunity to tailor and, most importantly, test theories from landscape and invasion ecology on microbial terrain.

虽然生物多样性生态系统功能（BEF）的争论已经大大推进了宏观生物学和理论生态学，但核心问题仍然是BEF耦合是否（以及如何）适用于微生物世界。由于微生物在自然和工程生态系统中的核心作用，这具有巨大的生态和社会意义。该提案旨在研究生物膜生物多样性与其大规模生态系统后果之间的关系。生物膜是基质封闭的社区，代表了大多数水生生态系统中微生物生命的主要形式，但他们的理解显着落后于他们的水生生态系统。我们将通过从景观生态学中获取概念知识，将生物膜研究置于明确的空间背景中。建模和实验之间的对话，这将使我们能够开发一个多尺度的计算模型，可以量化生物膜的入侵性和多样性，流体动力学混合和群体感应之间的相互作用在一系列不同的空间尺度。我们将从小的空间尺度（<0.01米）开始，并以最简单的假设，即来自同质源社区的完全随机社区组合不受混合和通信的影响。然后，我们将系统地提高规模（> 1000米），通过连续增加生物膜表面形貌，分散，流体动力学和群体感应的复杂性，并通过比较模型预测与实验观察。最终，我们将把溪流中的硝化菌生物多样性与氮循环联系起来，并输出到更大的下游生态系统。COMIX将大大有助于弥合微生物学和生态学之间的概念差距，推进跨尺度微生物生态学的数学建模，并将是一个独特的机会，可以定制，最重要的是，测试微生物地形上的景观和入侵生态学理论。

项目成果

Headwaters are critical reservoirs of microbial diversity for fluvial networks.

• DOI: 10.1098/rspb.2013.1760
• 发表时间: 2013-11-22
• 期刊: Proceedings. Biological sciences
• 作者: Besemer K;Singer G;Quince C;Bertuzzo E;Sloan W;Battin TJ
• 通讯作者: Battin TJ

Spatial-temporal survey and occupancy-abundance modeling to predict bacterial community dynamics in the drinking water microbiome.

• DOI: 10.1128/mbio.01135-14
• 发表时间: 2014-05-27
• 期刊: mBio
• 影响因子: 6.4
• 作者: Pinto AJ;Schroeder J;Lunn M;Sloan W;Raskin L
• 通讯作者: Raskin L

Neutral mechanisms and niche differentiation in steady-state insular microbial communities revealed by single cell analysis.

• DOI: 10.1111/1462-2920.14437
• 发表时间: 2019-01
• 期刊: Environmental microbiology
• 影响因子: 5.1
• 作者: Liu Z;Cichocki N;Hübschmann T;Süring C;Ofiţeru ID;Sloan WT;Grimm V;Müller S
• 通讯作者: Müller S

A Keystone Methylobacterium Strain in Biofilm Formation in Drinking Water

饮用水中生物膜形成的关键甲基杆菌菌株

• DOI: 10.3390/w9100778
• 发表时间: 2017
• 期刊: Water
• 影响因子: 3.4
• 作者: Tsagkari E