Identifying the physiological actions of calcitonin

确定降钙素的生理作用

• 批准号: nhmrc : 1058189
• 负责人: A/Pr Rachel Davey
• 金额: $ 45.55万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identifying-physiological-actions-calcitonin/454655
• 关键词: Identifying; physiological; actions; calcitonin

Calcitonin is a hormone whose main action has long been regarded as the slowing down of bone breakdown, however, its importance in human physiology is unknown. The aim of this study is to understand the role of calcitonin in regulating bone formation and protecting the skeleton in times of calcium stress, such as lactation. These results will greatly advance our understanding of the control of bone and calcium homeostasis, which will have implications for the treatment of bone disorders.

降钙素是一种激素，其主要作用一直被认为是减缓骨骼分解，然而，它在人体生理学中的重要性尚不清楚。本研究的目的是了解降钙素在钙应激时期（如哺乳期）在调节骨形成和保护骨骼中的作用。这些结果将极大地促进我们对骨和钙稳态控制的理解，这将对骨疾病的治疗产生影响。