Biostatistics Core

生物统计学核心

• 批准号: 7727453
• 负责人: Ann Laura Oberg
• 金额: $ 21.88万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7727453
• 关键词: Adverse event; Animal Model; Archives; Area; Arts; Basic Science; Biostatistics Core; Clinic; Clinical; Clinical Trials; Collaborations; Complement; Country; Data; Data Analyses; Databases; Development; Ensure; Epidemiologic Studies; Gene Mutation; Genes; Human Resources; Immunologics; Information Management; Institution; Instruction; Knowledge; Malignant neoplasm of ovary; Manuscripts; Methods; Molecular; Monitoring Clinical Trials; Nature; Preparation; Procedures; Program Research Project Grants; Quality Control; Registries; Reproduction spores; Research; Research Design; Research Infrastructure; Research Personnel; Resources; System; Testing; Time; abstracting; career development; computerized data processing; data management; experience; innovation; member; patient registry; programs; research study

The Biostatistics Core provides stafisfical collaborafion and data management support for each of the SPORE projects, the Developmental Research Program projects, the Career Development Program, and the other Cores. The Biostafistics Core prepared the stafisfical plans for each of the four projects, will provide data management for each of the projects and adverse event monitoring for the clinical trials, and will prepare data summaries for manuscript preparation. The Biostatistics Core has been very active in preparing the stafistical plans for each of the four projects in this SPORE Application. Each of the projects presented in this applicafion reflects input from members of the Biostatistics Core on study design and analysis plan. These projects require a wide range of approaches and analyses. The Biostafistics Core builds upon the innovative and time-tested procedures and systems developed by Mayo Clinic, one of the largest stafisfical groups in the country whose members have collaborated on more than 13,000 clinical and basic science research studies since 1966. The Biostafistics Core has the capability to provide statistical support across different fields. Including molecular epidemiologic studies, basic science with translational, immunologic, and correlafive studies, gene microarray, clinical trials, gene and mutation discovery, and informafion management. The comprehensive nature of the Biostafisfics Core assures each SPORE invesfigator access to statistical expertise that includes collaborative development of study designs and analysis plans, state-of-the-art data analysis and Interpretation, data management resources, and abstract and manuscript preparation. The Biostafisfics Core also provides a mechanism for the management and integration of both existing and newly collected data through consistent and compatible data handling. Areas of support include database development, data form development and processing, data collecfion and entry, data archiving, quality control, and management of information relafing to the projects and cores. This Core complements and assists the efforts of the Animal Model Core and the Biospecimens and Patient Registry Core by providing superior data management and experience with fissue registries. The strengths of the Biostatistics Core are our collaboration with each of the projects and cores, the knowledge of and ability to ufilize the established research databases, the operational and statistical infrastructure already in place in the institution, and the breadth of expertise provided by Biostatistics Core personnel. RELEVANCE (See instructions): Careful data management approaches and proper data analysis methods are required to ensure that the correct conclusions are made from a research study. The Biostafistics Core will provide expertise and support to ovarian cancer researchers in the areas of study design, data management, and data analysis.

生物统计学核心为每一个生物统计学领域提供了统计协作和数据管理支持。 SPORE项目、发展研究计划项目、职业发展计划和 其他核心生物统计学核心为四个项目中的每一个项目准备了统计计划，将提供 每个项目的数据管理和临床试验的不良事件监测，并将 准备数据摘要以备稿件。生物统计学核心一直非常活跃， 准备本SPORE应用程序中四个项目的统计计划。每个项目 本申请中所列内容反映了生物统计学核心成员对研究设计的输入， 分析计划。这些项目需要广泛的方法和分析。生物统计学的核心 基于马约诊所开发的创新和经过时间考验的程序和系统， 全国最大的科学团体，其成员合作了13，000多个临床和 自1966年以来的基础科学研究。生物统计学核心能够提供统计数据， 支持不同领域。包括分子流行病学研究，基础科学与转化， 免疫学和相关研究，基因微阵列，临床试验，基因和突变发现， 信息化管理Biostafisfics核心的全面性确保了每个孢子 投资者获得统计专业知识，包括合作开发研究设计， 分析计划、最先进的数据分析和解释、数据管理资源和摘要 和手稿准备。Biostafisfics核心还提供了一种管理机制， 通过一致和兼容的数据处理，整合现有和新收集的数据。地区 包括数据库开发、数据表格开发和处理、数据收集和输入， 资料归档、质量控制、项目及岩心相关资料管理。这一核心 补充和协助动物模型中心和生物标本和患者登记处的工作 通过提供上级数据管理和fissue注册中心经验，获得核心。的长处 生物统计学核心是我们与每个项目和核心的合作， 利用已建立的研究数据库， 机构，以及生物统计核心人员提供的专业知识的广度。 相关性（参见说明）： 需要谨慎的数据管理方法和适当的数据分析方法，以确保 通过研究得出正确的结论。生物统计学核心将提供专业知识， 在研究设计、数据管理和数据分析方面为卵巢癌研究人员提供支持。