Biostatistics Core

生物统计核心提供统计协作和数据管理支持 孢子项目、开发项目和其他核心。在这场竞争性的更新中， 生物统计核心一直非常积极地为每个项目准备统计计划。此外， 生物统计核心继续为每个项目提供数据管理、不良事件监测 用于临床试验，并为手稿准备数据摘要。这些项目的跨度很大 一系列的方法和分析。生物统计学的核心建立在创新和经过时间考验的 由梅奥诊所开发的程序和系统，该诊所是美国最大的统计组织之一，其 自1932年以来，成员们一直在临床和基础科学研究方面进行合作。生物统计学 CORE将在不同领域提供统计支助，包括流行病学研究、基础科学 包括翻译和免疫学相关研究、基因表达和成像、临床试验、基因 以及突变发现、下一代测序和信息管理。全面的 生物统计核心的性质确保每个孢子调查员都能获得统计专业知识，包括 协作开发研究设计和分析计划、最先进的数据分析和 口译、数据管理资源、摘要和手稿准备。生物统计学的核心 还提供了管理和集成现有数据和新收集的数据的机制 通过一致和兼容的数据处理、数据库开发、数据表单开发和 处理、数据收集和录入、数据存档、质量控制和有关信息的管理 到项目和核心。这一核心补充和协助了临床研究和组织的努力 通过提供卓越的数据管理和组织登记处的体验，我们可以获得更多的核心数据。的优势所在 生物统计学的核心是我们与每个项目和核心的合作，利用 建立中央研究数据库以及已在#年的业务和统计基础设施 在孢子的位置，和生物统计核心人员提供的专业知识的广度。

The Biostatistics Core provides statistical collaboration and data management support for each of the SPORE projects, the developmental projects, and the other Cores. In this competitive renewal, the Biostatistics Core has been very active in preparing the statistical plan for each Project. In addition, the Biostatistics Core continues to provide data management for each of the projects, adverse event monitoring for the clinical trials, and prepares data summaries for manuscript preparation. These projects span a wide range of approaches and analyses. The Biostatistics Core builds upon the innovative and time-tested procedures and systems developed by Mayo Clinic, one of the largest statistical groups in the country whose members have collaborated on clinical and basic science research studies since 1932. The Biostatistics Core will provide statistical support across different fields, including epidemiological studies, basic sciences including translational and immunologic correlative studies, gene expression and imaging, clinical trials, gene and mutation discovery, next generation sequencing and information management. The comprehensive nature of the Biostatistics Core assures each SPORE investigator access to statistical expertise that includes collaborative development of study designs and analysis plans, state of the art data analysis and interpretation, data management resources, and abstract and manuscript preparation. The Biostatistics Core also provides a mechanism for the management and integration of both existing and newly collected data through consistent and compatible data handling, database development, data form development and processing, data collection and entry, data archiving, quality control, and management of information relating to the projects and cores. This Core complements and assists the efforts of the Clinical Research and Tissue Cores by providing superior data management and experience with tissue registries. The strengths of the Biostatistics Core are our collaboration with each of the projects and cores, the ability to utilize the established centralized research database as well as the operational and statistical infrastructure already in place in the SPORE, and the breadth of expertise provided by Biostatistics Core personnel.