Developmental Research Program

发展研究计划

• 批准号: 7715194
• 负责人: CLARA D BLOOMFIELD
• 金额: $ 11.23万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7715194
• 关键词: Advertisements; Advertising; Applications Grants; Area; Automobile Driving; Basic Science; Clinical; Complement; Development; Diagnosis; Discipline; Documentation; Elements; Evaluation; Funding; Grant; Hispanics; Institution; Investigation; Leadership; Mentors; Minority; Peer Review; Physicians; Pilot Projects; Population Sciences; Positioning Attribute; Prevention; Process; Program Research Project Grants; Reproduction spores; Research; Research Personnel; Resources; Scientist; Selection Criteria; Source; Therapeutic; Translational Research; Woman; Work; expectation; innovation; interest; leukemia; new technology; outcome forecast; programs

The Developmental Research Program (DRP) is a critical component of the Leukemia SPORE application; it effectively demands the exploration of new ideas as pilot projects, development of new resources and implementation of new technologies that are the driving elements of translational research. This effort also provides the SPORE investigators with a renewable source of projects that can fully develop and replace existing SPORE projects that have been completed or have not fulfilled specific translational expectations. Rigorous solicitation of developmental proposals, along with a well-defined peer review process will be critical for implementation of an effective DRP. The DRP will seek to fund a broad range oif proposals that will enhance our existing SPORE Projects, from basic science investigation, population science, and innovative approaches toward prevention, diagnosis, and prognosis as well as experimental therapeutics. The Leukemia SPORE Executive Committee has selected Drs. Michael R. Grever and Clara D. Bloomfield to be Co-Leaders of the DRP. These investigators have important leadership positions in the OSUCCC and nationally in the field of leukemia research, with over 50 years of collectively mentoring junior people in this discipline. The DRP proposal provides evidence of our significant effort to support.pilot projects within the DRP, including strong institutional commitment of dollars and space in order to take maximum advantage of new research opportunities. The DRP provides documentation for our advertisement and solicitation plan, with special emphasis on women and minority physicians and scientists to participate in this endeavor. This is exemplified by two woman and two Hispanic minorities leading potential DRP projects. Additionally, our DRP is focused on involving other institutions with expertise to complement the research program in our SPORE as exemplified by two non-OSU DRP projects. The DRP leaders have developed a rigorous yet efficient review process with selection criteria that should prioritize those innovative and feasible applications that show either synergy with existing work and emphasis in areas that will ultimately broaden the scope of our Leukemia SPORE, while again emphasizing the recruitment of women and minorities to the DRP. Finally, the DRP will provide a broad plan for co-mentoring the funded DRP investigators, in order that they obtain input from basic, clinical, and biostatistical leaders, thus optimizing the likelihood of developing the project into a full SPORE project or other nationally funded independent grant.

发展研究计划（DRP）是白血病孢子应用的关键组成部分； 它有效地要求探索新思想作为试点项目，开发新资源和 实施新技术是转化研究的驱动因素。这也是如此 为孢子调查人员提供可再生的项目来源，可以完全开发和替换 现有的孢子项目已经完成或尚未满足特定的翻译期望。 严格对发展建议的招标，以及定义明确的同行评审过程 对于实施有效的DRP至关重要。 DRP将寻求资助广泛的OIF建议 将从基础科学调查，人群科学和 预防，诊断和预后以及实验疗法的创新方法。 白血病孢子执行委员会选择了Drs。 Michael R. Grever和Clara D. Bloomfield 成为DRP的共同领导者。这些调查人员在OSUCCC和 在白血病研究领域，全国范围内拥有超过50年的共同指导初级人员 纪律。 DRP提案提供了我们支持的巨大努力的证据。 DRP，包括美元和空间的强大机构承诺，以最大程度地利用 新的研究机会。 DRP为我们的广告和招标计划提供文档， 特别强调妇女和少数族裔医生和科学家参加这项工作。这 两名妇女和两个西班牙裔少数族裔都领导了潜在的DRP项目。另外，我们的 DRP专注于参与具有专业知识的其他机构，以补充我们的研究计划 孢子由两个非OSU DRP项目举例说明。 DRP领导人已经建立了严格的 有效的审核过程具有选择标准，应优先考虑这些创新和可行 显示出与现有工作协同作用的应用，并重点是最终将扩大的领域 我们白血病孢子的范围，同时再次强调招募妇女和少数民族 DRP。最后，DRP将为资助的DRP调查人员提供广泛的计划，以 他们从基本，临床和生物统计领导者那里获得投入，从而优化了 将该项目开发为一个完整的孢子项目或其他全国资助的独立赠款。