Developmental Research Program

发展研究计划

• 批准号: 7715194
• 负责人: CLARA D BLOOMFIELD
• 金额: $ 11.23万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7715194
• 关键词: Advertisements; Advertising; Applications Grants; Area; Automobile Driving; Basic Science; Clinical; Complement; Development; Diagnosis; Discipline; Documentation; Elements; Evaluation; Funding; Grant; Hispanics; Institution; Investigation; Leadership; Mentors; Minority; Peer Review; Physicians; Pilot Projects; Population Sciences; Positioning Attribute; Prevention; Process; Program Research Project Grants; Reproduction spores; Research; Research Personnel; Resources; Scientist; Selection Criteria; Source; Therapeutic; Translational Research; Woman; Work; expectation; innovation; interest; leukemia; new technology; outcome forecast; programs

The Developmental Research Program (DRP) is a critical component of the Leukemia SPORE application; it effectively demands the exploration of new ideas as pilot projects, development of new resources and implementation of new technologies that are the driving elements of translational research. This effort also provides the SPORE investigators with a renewable source of projects that can fully develop and replace existing SPORE projects that have been completed or have not fulfilled specific translational expectations. Rigorous solicitation of developmental proposals, along with a well-defined peer review process will be critical for implementation of an effective DRP. The DRP will seek to fund a broad range oif proposals that will enhance our existing SPORE Projects, from basic science investigation, population science, and innovative approaches toward prevention, diagnosis, and prognosis as well as experimental therapeutics. The Leukemia SPORE Executive Committee has selected Drs. Michael R. Grever and Clara D. Bloomfield to be Co-Leaders of the DRP. These investigators have important leadership positions in the OSUCCC and nationally in the field of leukemia research, with over 50 years of collectively mentoring junior people in this discipline. The DRP proposal provides evidence of our significant effort to support.pilot projects within the DRP, including strong institutional commitment of dollars and space in order to take maximum advantage of new research opportunities. The DRP provides documentation for our advertisement and solicitation plan, with special emphasis on women and minority physicians and scientists to participate in this endeavor. This is exemplified by two woman and two Hispanic minorities leading potential DRP projects. Additionally, our DRP is focused on involving other institutions with expertise to complement the research program in our SPORE as exemplified by two non-OSU DRP projects. The DRP leaders have developed a rigorous yet efficient review process with selection criteria that should prioritize those innovative and feasible applications that show either synergy with existing work and emphasis in areas that will ultimately broaden the scope of our Leukemia SPORE, while again emphasizing the recruitment of women and minorities to the DRP. Finally, the DRP will provide a broad plan for co-mentoring the funded DRP investigators, in order that they obtain input from basic, clinical, and biostatistical leaders, thus optimizing the likelihood of developing the project into a full SPORE project or other nationally funded independent grant.

发展研究计划（DRP）是白血病孢子应用程序的关键组成部分; 它有效地要求探索新的想法作为试点项目，开发新的资源， 新技术的实施是转化研究的驱动因素。这一努力也 为SPORE调查人员提供了一个可再生的项目来源，可以完全开发和取代 现有的SPORE项目已经完成或尚未实现特定的转化预期。 严格征求发展建议，沿着明确的同行审查程序， 这对实施有效的DRP至关重要。DRP将寻求资助广泛的oif提案， 将加强我们现有的SPORE项目，从基础科学调查，人口科学， 预防、诊断和预后以及实验治疗的创新方法。 白血病孢子执行委员会选择了迈克尔R。Grever和Clara D.布卢姆菲尔德 成为DRP的联合领导人。这些调查人员在OSUCCC中担任重要领导职务， 在全国范围内从事白血病研究领域，50多年来一直在这一领域集体指导初级人员 纪律建议书证明我们已作出重大努力，支持 减少灾害风险方案，包括在资金和空间方面作出强有力的机构承诺，以便最大限度地利用 新的研究机会。DRP为我们的广告和征集计划提供文档， 特别强调妇女和少数民族医生和科学家参与这一奋进。这 两名妇女和两名西班牙裔少数民族领导着潜在的DRP项目。此外，我们的 DRP专注于让其他具有专业知识的机构参与进来，以补充我们的研究计划。 以两个非俄勒冈州立大学DRP项目为例。DRP领导人制定了一项严格但 高效率的审查进程，选择标准应优先考虑那些创新和可行的 这些应用与现有工作具有协同作用，并强调最终将扩大 我们的白血病孢子的范围，同时再次强调妇女和少数民族的招聘， 的DRP。最后，DRP将为共同指导受资助的DRP调查人员提供广泛的计划，以便 他们从基础，临床和生物统计学领导者那里获得输入，从而优化 将该项目发展为一个完整的SPORE项目或其他国家资助的独立赠款。