SAFETY AND BETA-HCG + ERYTHROPOIETIN IN ACUTE STROKE

急性中风的安全性和 β-HCG 促红细胞生成素

• 批准号: 7951050
• 负责人: STEVEN Michael CRAMER
• 金额: $ 0.06万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-12-01 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951050
• 关键词: Adult; Affect; Behavior; Brain; Brain Infarction; Cause of Death; Chorionic Gonadotropin, beta Subunit; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Country; Erythropoietin; Funding; Grant; Infarction; Institution; Left; Life; Nature; Patients; Recovery; Research; Research Personnel; Resources; Safety; Severities; Source; Stroke; United States National Institutes of Health; acute stroke; artery occlusion; attributable mortality; cerebral artery; disability; human morbidity; mortality; post stroke

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Stroke remains a major source of human morbidity and mortality. Stroke is the third leading cause of death in the Western countries, with approximately 1 in 15 deaths attributable to stroke, and the second leading cause of death worldwide. Approximately 85% of patients survive an acute stroke, living an average of seven years thereafter. Most are left with significant disability1-3, which reduces activities and participation. Stroke most frequently is caused by an ischemic infarct due to thromboembolic cerebral artery occlusion and, thus, can affect all aspects of brain function. The nature and severity of post-stroke deficits vary widely. Over the weeks-months following a brain infarction, most patients do show some spontaneous improvement in those behaviors affected by stroke4-6. However, this recovery is highly variable and generally incomplete. As a result, stroke is the leading cause of adult disability in the U.S. and many other countries.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 中风仍然是人类发病率和死亡率的主要来源。 中风是西方国家的第三大死亡原因，约1/15的死亡归因于中风，并且是全球第二大死亡原因。 大约85%的患者在急性中风后存活，平均寿命为7年。 大多数人留下了严重的残疾1 -3，减少了活动和参与。 中风最常见的是由血栓栓塞性脑动脉闭塞引起的缺血性梗死，因此可以影响脑功能的各个方面。 中风后缺陷的性质和严重程度差异很大。 在脑梗死后的数周至数月内，大多数患者确实在受中风影响的行为方面表现出一些自发性改善4 -6。 然而，这种恢复是高度可变的，通常是不完整的。 因此，中风是美国和许多其他国家成人残疾的主要原因。