THE EFFECTS OF RESISTIVE OR AEROBIC EXERCISE AND A NUTRITION (RAN) PROGRAM

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项拟议的研究的具体目的是比较两种类型的锻炼计划和营养干预对身体成分、血压、功能状态和情绪的影响。数据将在基线(第0周)和第10周收集。受试者将被允许继续研究50周。那些在最初的10周后继续锻炼的受试者，将在他们的锻炼方案中增加另一种锻炼形式。这些受试者将每10周接受一次身体成分、血压、机能状态和情绪变化的评估。这部分干预的目的将是评估有氧运动和耐力运动相结合的长期变化。将使用双能X射线骨密度仪(DEXA)测量身体脂肪分布、全身骨密度以及腰椎和臀部的骨密度。受试者将在UMB GCRC接受DEXA扫描，以了解体脂分布、全身骨密度以及基线时腰椎和髋部的骨密度。在第10周，他们将在UMB GCRC接受DEXA扫描，仅检查身体脂肪分布。如果受试者坚持锻炼50周，他们将在UMB GCRC接受第三次也是最后一次DEXA扫描，以了解体脂分布、全身骨密度以及腰椎和髋部的骨密度。我们将检查从基线到第10周的总体脂的变化，并在第50周再次检查。此外，我们将在基线和第50周检测全身骨密度和腰椎和髋部的骨密度。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The specific aim of the proposed study is to compare the effects of a two types of exercise programs and a nutrition intervention on body composition, blood pressure, functional status and mood. Data will be collected at baseline (week 0) and at week 10. Subjects will be allowed to continue in the study for up 50 weeks. Those subjects who continue beyond the initial 10-week period will have the alternate form of exercise added to their regime. These subjects will be assessed every 10-weeks for changes in body composition, blood pressure, funtional status and mood. The purpose of this portion of the intervention will be to assess the long term changes associated with a combination of aerobic and resistive exercise. Body fat distribution, total body bone density and bone density in the lumbar spine and hip will be measured using a Dual Energy X-Ray Absorptiometry (DEXA). Subjects will undergo a DEXA scan at the UMB GCRC for body fat distribution, total body bone density and bone density in the lumbar spine and hip at baseline. At week 10, they will undergo a DEXA scan at the UMB GCRC for body fat distribution only. If subjects remain exercising for 50 weeks, they will undergo a third and final DEXA scan at the UMB GCRC for body fat distribution, total body bone density and bone density in the lumbar spine and hip. We will examine the change in total body fat from baseline to week 10 and again at week 50. In addition we will examine total body bone density and bone density in the lumbar spine and hip at baseline and week 50.