THE EFFECT OF AEROBIC EXERCISE ON BLOOD PRESSURE AMONG AFRICAN-AMERICAN WOMEN

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这将是一项针对130名患有高血压(收缩/舒张压[B/P]大于或等于140/90毫米汞柱或目前正在服用降压药的非裔美国女性)的多中心、平行的随机对照试验。这项拟议的随机对照试验的主要目的是确定12周有氧运动对患有高血压的非裔美国女性的降压效果。这项研究的第二个目的是测试12周的有氧运动是否改善了患有高血压的非裔美国女性的下列心血管疾病风险因素的水平：总胆固醇、甘油三酯、脂蛋白(HDL和LDL)水平、血糖和胰岛素。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This will be a multi-center, parallel arm, randomized controlled trial among 130 African-American women with hypertension (systolic/diastolic blood pressure [B/P] greater then or equal to 140/90mmHg or currently taking anti-hypertensive medications). The primary aim of the proposed randomized, controlled trial is to determine the BP lowering effect of 12 weeks of aerobic exercise among African-American women with established hypertension. The secondary aim of this study is to test whether 12 weeks of aerobic exercise improves the levels of the following cardiovascular disease risk factors among African-American women with hypertension: total cholesterol, triglycerides, lipoprotein (HDL and LDL) levels, serum glucose and insulin.