ATN 063: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF THE SAFETY A

ATN 063：安全性的随机、双盲、安慰剂对照试验

• 批准号: 7951132
• 负责人: LAWRENCE James D'ANGELO
• 金额: $ 1.11万
• 依托单位: CHILDREN'S RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-12-01 至 2010-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951132
• 关键词: Adolescent; Anti-Retroviral Agents; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; HIV Infections; Institution; Kidney; N-telopeptide; Plasma; Population; Randomized; Research; Research Personnel; Resources; Safety; Source; Supplementation; Tenofovir; Testing; Treatment Protocols; United States National Institutes of Health; Vitamin D; bone turnover; double-blind placebo controlled trial; improved; inorganic phosphate; young adult

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to test the hypothesis that in a population of adolescents and young adults with HIV infection who are being treated with tenofovir as part of an antiretroviral combination regimen, vitamin D supplementation will decrease renal phosphate loss, increase plasma phosphate, decrease plasma PTH, and improve markers of bone turnover, including a decrease in plasma N-telopeptide and BAP.

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