SINGLE-SHOT METABOLIC IMAGING OF THE RAT
大鼠的单次代谢成像
基本信息
- 批准号:7955419
- 负责人:
- 金额:$ 1.8万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-06-01 至 2010-05-31
- 项目状态:已结题
- 来源:
- 关键词:Chemical Shift ImagingComputer Retrieval of Information on Scientific Projects DatabaseDataFundingGrantImageInstitutionMetabolicMetabolismNaturePerformancePyruvatePyruvatesRattusResearchResearch PersonnelResolutionResourcesSamplingSignal TransductionSliceSourceTechniquesTechnologyTimeUnited States National Institutes of HealthWidthWorkdesignin vivonovel strategies
项目摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
Hyperpolarization of metabolically active substrates such as 13C1-pyruvate permits new approaches to the investiga¿tion of in vivo metabolism using MRS and chemical shift imaging. However, the transient nature of the signal amplification necessitates fast data sampling techniques. The aim of this work was to achieve single-shot metabolic imaging in the rat in vivo by using undersampled 13C spiral CSI (spCSI) in combination with a high-performance gradient insert.
The implemented sequence consists of a slice(z)-selective excitation and a spiral readout gradient for combined spatial(xy)-spectral(f) encoding. The spiral waveforms were designed for a FOV of 48¿48 mm2 with a nominal 3¿3-mm2 in-plane resolution. The insert gradients allowed a spectral width (SW) of 298 Hz in single-shot mode. With 32 echoes acquired after excitation, the total acquisition time (Tacq) was less than 120 ms.
这个子项目是众多研究子项目之一
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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DIRK MAYER其他文献
DIRK MAYER的其他文献
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{{ truncateString('DIRK MAYER', 18)}}的其他基金
FAST PARALLEL SPIRAL CSI AT 3 TESLA USING ITERATIVE SENSE RECONSTRUCTION
使用迭代感知重建的 3 特斯拉快速并行螺旋 CSI
- 批准号:
7722883 - 财政年份:2008
- 资助金额:
$ 1.8万 - 项目类别:
IN VIVO DTI OF RAT BRAIN ON A 3T MR SYSTEM W/INSERT GRADIENTS
在 3T MR 系统上插入梯度的大鼠大脑体内 DTI
- 批准号:
7601883 - 财政年份:2007
- 资助金额:
$ 1.8万 - 项目类别:
FAST 1H MISSING-PULSE SSFP CHEMICAL SHIFT IMAGING OF THE HUMAN BRAIN AT 7 TESLA
7 特斯拉下人脑的快速 1 小时缺失脉冲 SSFP 化学位移成像
- 批准号:
7601932 - 财政年份:2007
- 资助金额:
$ 1.8万 - 项目类别:
FAST PARALLEL SPIRAL CSI AT 3 TESLA USING ITERATIVE SENSE RECONSTRUCTION
使用迭代感知重建的 3 特斯拉快速并行螺旋 CSI
- 批准号:
7601931 - 财政年份:2007
- 资助金额:
$ 1.8万 - 项目类别:
RAPID SPIRAL CSI IMAGING USING CG RECONSTRUCTION
使用 CG 重建的快速螺旋 CSI 成像
- 批准号:
7601926 - 财政年份:2007
- 资助金额:
$ 1.8万 - 项目类别:
13C, SPIRAL CHEMICAL SHIFT IMAGING, SPECTRAL UNDERSAMPLING, PYRUVATE, LACTATE
13C,螺旋化学位移成像,光谱欠采样,丙酮酸盐,乳酸盐
- 批准号:
7601881 - 财政年份:2007
- 资助金额:
$ 1.8万 - 项目类别:
IN VIVO DTI OF RAT BRAIN ON A 3T MR SYSTEM W/INSERT GRADIENTS
在 3T MR 系统上插入梯度的大鼠大脑体内 DTI
- 批准号:
7358782 - 财政年份:2006
- 资助金额:
$ 1.8万 - 项目类别:
INTEGRATIVE NEUROSCIENCE INITIATIVE ON ALCOHOLISM (INIA)
关于酗酒的综合神经科学倡议 (INIA)
- 批准号:
7358784 - 财政年份:2006
- 资助金额:
$ 1.8万 - 项目类别:
13C, SPIRAL CHEMICAL SHIFT IMAGING, SPECTRAL UNDERSAMPLING, PYRUVATE, LACTATE
13C,螺旋化学位移成像,光谱欠采样,丙酮酸盐,乳酸盐
- 批准号:
7358767 - 财政年份:2006
- 资助金额:
$ 1.8万 - 项目类别: