RAPID SPIRAL CSI IMAGING USING CG RECONSTRUCTION

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 螺旋化学位移成像（CSI）通过采集时域数据同时沿沿着两个空间维度播放螺旋梯度波形来减少CSI实验的扫描时间。这实现了空间和频谱信息的同时编码，并且理论上允许利用单个激励采集完整的2D CSI数据集。然而，对于大多数应用，对最大梯度强度和转换速率的限制通常使得需要多个激励，其中数据采集的开始被移位（光谱交错）或螺旋k空间轨迹被旋转（空间交错）。梯度限制在更高的场强下甚至是一个问题，因为化学位移的分散增加。虽然并行成像技术通常甚至在非笛卡尔成像中使用以加速采集，但到目前为止，它们仅应用于使用常规相位编码和回波平面光谱成像的CSI。 在使用C13标记的示踪剂的分子成像应用中，快速读出是特别相关的。在这里，快速采集有助于对心肌等组织进行成像，并且还允许更好地监测C13示踪剂如何代谢的动力学。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Spiral chemical shift imaging (CSI) reduces the scan time of a CSI experiment by acquiring the time domain data while playing out spiral gradient waveforms along two spatial dimensions. This achieves the simultaneous encoding of both spatial and spectral information and theoretically permits the acquisition of a complete 2D CSI data set with a single excitation. However, for most applications, limitations on maximum gradient strength and slew rate usually make multiple excitations necessary in which either the start of the data acquisition is shifted (spectral interleaves) or the spiral k-space trajectories are rotated (spatial interleaves). Gradient limitations are even more a problem at higher field strength because of the increased dispersion of the chemical shift. While parallel imaging techniques are commonly used even in non-Cartesian imaging to speed up the acquisition, so far, they have been only applied to CSI using conventional phase encoding and echo planar spectroscopic imaging. A rapid readout is of particular relevance in molecular imaging applications using C13-labelled tracers. Here, a rapid acquisition helps to image tissue like the myocardium and also allows one to better monitor the kinetics how C13-tracers gets metabolized.