WAXS CAMERA COMMISSIONING

WAXS 相机调试

• 批准号: 7954914
• 负责人: LIANG GUO
• 金额: $ 0.65万
• 依托单位: ILLINOIS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7954914
• 关键词: Biophysics; Buffers; Computer Retrieval of Information on Scientific Projects Database; Development; Funding; Grant; Helium; Institution; Length; Modification; Monitor; Performance; Research; Research Personnel; Resources; Signaling Protein; Solutions; Source; Testing; United States National Institutes of Health; Vacuum; instrument

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. One of the proposed core developments was a dedicated WAXS instrument with a wider q  range than our present instrument. A new WAXS camera of flight path 430 mm in helium was tested for its performance. It was found that the 430 mm path length is too long to be used in helium; background scattering from helium cannot be properly removed. Modifications are in progress so that the WAXS camera may be used in vacuum. A photo-diode array beam intensity monitor was also tested with scattering signals of protein solution and buffer background and the performance of the intensity monitor was evaluated. The results show that further improvements are needed for the intensity monitor to be used in actual SAXS applications.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 其中一个核心发展是一个专用的WAXS仪器，具有更广泛的q  比我们现在的仪器更大。对一台新研制的430 mm飞行轨迹的WAXS相机进行了性能测试。 结果发现，430毫米的路径长度太长，不能用于氦;背景散射从氦不能被适当地删除。 正在进行改进，以便WAXS照相机可以在真空中使用。利用蛋白质溶液和缓冲液背景的散射信号对光电二极管阵列光束强度监测器进行了测试，并对强度监测器的性能进行了评价。 结果表明，强度监测器需要进一步改进，以用于实际的SAXS应用。