PDU MICROCOMPARTMENTS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 PDU微室是一种蛋白质亚细胞结构，在肠沙门氏菌中作为1，2-丙二醇代谢的细胞器。它将几种相关的酶包裹在一个由数千个蛋白质亚基组成的外壳中。最近对羧体的结构研究得出结论，来自该微室的主要壳蛋白形成六聚体，这些六聚体填充到构成壳面的层中。 这些子项目的目标是阐明形成PDU微室的蛋白质的结构。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Pdu microcompartment is a proteinaceous, subcellular structure that serves as an organelle for the metabolism of 1,2-propanediol in /Salmonella enterica/. It encapsulates several related enzymes within a shell composed of a few thousand protein subunits. Recent structural studies on the carboxysome, a related microcompartment involved in CO_2 fixation, have concluded that the major shell proteins from that microcompartment form hexamers that pack into layers comprising the facets of the shell. The goal of these subproject is to elucidate the structure of proteins that form of the Pdu microcompartment.