STRUCTURE FUNCTION STUDIES OF RIBOSOMAL BIOGENESIS ENZYMES

核糖体生物合成酶的结构功能研究

• 批准号: 7955150
• 负责人: Hong Li
• 金额: $ 0.43万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7955150
• 关键词: Biochemical; Biogenesis; Complex; Computer Retrieval of Information on Scientific Projects Database; Enzymes; Funding; Grant; Guide RNA; Institution; Methods; Research; Research Personnel; Resources; Ribosomes; Small RNA; Source; Structure; United States National Institutes of Health; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Ribosome is matured by a complex set of factors including two classes of small RNA-guided enzymes. We are investigating the structure and function of these RNA-guided enzymes using crystallographic and biochemical methods.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 核糖体的成熟是由一系列复杂的因素，包括两类小RNA引导的酶。我们正在使用晶体学和生物化学方法研究这些RNA引导的酶的结构和功能。