Core D – Biostatistics Core

核心 D — 生物统计学核心

• 批准号: 10441218
• 负责人: Hong Li
• 金额: $ 7.48万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10441218
• 关键词: Address; Basic Science; Biometry; Biostatistics Core; Biostatistics Shared Resource; Cancer Center; Communication; Complex; Data; Data Analyses; Data Analytics; Data Collection; Data Display; Ensure; Evaluation Research; Faculty; Fertilization; Formulation; Fostering; Generations; Human Resources; Investigation; Logistics; Maintenance; Malignant neoplasm of pancreas; Manuscripts; Medical; Oncology; Outcome; Output; Positioning Attribute; Preparation; Procedures; Program Research Project Grants; Publications; Reporting; Research; Research Design; Research Personnel; Resources; Role; Sample Size; Security; Services; South Carolina; Statistical Data Interpretation; Statistical Methods; Statistical Models; Testing; Translational Research; Universities; Visual; base; cancer cachexia; complex data; computerized data processing; data analysis pipeline; data exchange; data exploration; data integration; data management; data quality; data sharing; design; experimental study; member; novel; power analysis; programs; repository; statistics; success; tool

SUMMARY: CORE D The Biostatistics Core provides centralized and state-of-the-art support to meet the data management and analytic needs of the Program Project Grant. Core personnel have the necessary expertise in statistics to optimize the quantitative demands of the aims outlined in each project. Core centralization fosters bonds and communication between project leaders and statisticians, and facilitates matching of investigators with the most appropriate quantitative collaborators. In addition, centralizing this resource ideally positions the Core to initiate and promote interdisciplinary interactions among projects, and thus contributes to accelerating the bi -directional exchange between basic and translational science. Core personnel can also help investigators design new studies and test new hypotheses that may arise by cross-fertilization among related projects. The Core will be staffed by two statisticians, Dr. Hong Li (Core Leader) and Mr. Kent Armeson. Core biostatisticians are housed in the Biostatistics Shared Resource in the Hollings Cancer Center (HCC) at the Medical University of South Carolina (MUSC), an active and committed group of biostatistics faculty members broadly skilled in statistical methods in oncology research. By situating key Core personnel in MUSC’s HCC, all projects are guaranteed access to a robust tool kit to support quantitative needs. All Projects require support with respect to: experimental study design, including power analysis and sample size justification ; data collection, storage, and analysis; interpretation of output from complex statistical methods; and abstract and manuscript preparation. By providing research expertise and logistical support to the quantitative needs of each project, the Biostatistic s Core will contribute to professional, efficient and rigorous procedures for the generation, analysis and interpretation of data, which will be critical to the success of the Program Project Grant.

摘要：核心 D 生物统计核心提供集中和最先进的支持，以满足数据管理和 计划项目拨款的分析需求。核心人员拥有必要的统计专业知识， 优化每个项目中概述的目标的数量要求。核心集中化促进了纽带和 项目负责人和统计人员之间的沟通，并促进调查人员与最有经验的人的匹配 合适的定量合作者。此外，集中此资源可以理想地使核心启动 并促进项目之间的跨学科互动，从而有助于加速双向 基础科学和转化科学之间的交流。核心人员还可以帮助调查人员设计新的 研究并测试相关项目之间的交叉传播可能产生的新假设。核心将是 其工作人员包括两名统计学家，李红博士（核心领导者）和 Kent Armeson 先生。核心生物统计学家驻扎 南医科大学霍林斯癌症中心 (HCC) 生物统计学共享资源博士 Carolina (MUSC)，一个活跃且忠诚的生物统计学教员群体，拥有广泛的统计技能 肿瘤学研究方法。通过将关键核心人员安置在 MUSC 的 HCC，所有项目都有保障 获得强大的工具包来支持定量需求。所有项目都需要以下方面的支持： 实验性 研究设计，包括功效分析和样本量论证；数据收集、存储和分析； 对复杂统计方法输出的解释；以及摘要和手稿的准备。通过提供 为每个项目的定量需求提供研究专业知识和后勤支持，生物统计核心将 有助于专业、高效和严格的生成、分析和解释程序 数据，这对于计划项目拨款的成功至关重要。