Pilot/Exploratory Studies Core

试点/探索性研究核心

• 批准号: 7802717
• 负责人: STEPHANIE A STUDENSKI
• 金额: $ 9.13万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7802717
• 关键词: Adherence; Age; Aging; American; Area; Award; Development; Developmental Process; Electric Stimulation; Equilibrium; Ethics; Funding; Future; Goals; Grant; Interdisciplinary Study; Investigation; Monitor; NF-kappa B; Pilot Projects; Privacy; Process; Productivity; Research Methodology; Research Personnel; Resources; Role; Safety; Spinal Stenosis; Stem cells; Symptoms; Techniques; Walking; innovation; muscle aging; older patient; regenerative

The goal of the Pilot/Exploratory Studies Core is to promote innovative multidisciplinary research related to mobility, balance and aging. The P/ESC manages the process of promotion, application, review, award and monitoring for Pilot/Exploratory Studies and Developmental projects. Priorities for awards include relevance to the OAIC theme, potential for independent funding, new multidisciplinary collaboration and translational potential. Additional priorities for Development Projects are potential to advance research methods in the area of mobility, balance and aging, degree of innovation and potential for incorporation into OAIC future studies. In order to make the most efficient use of resources, projects that serve as add-ons to existing funded studies are encouraged. Proposed first year pilot studies include PES-i: Role of NF-kB in stem cells in aging, PES-2: Pre-operative treatment with electrical stimulation enhances aged muscle regenerative capacity and return to functional mobility post-operatively, PES-3 Investigation into the Mechanisms of Symptom Relief with Forward Flexion in Older Patients with Spinal Stenosis and PES-4:Variability, Stability and Smoothness of Walking.

试点/探索性研究核心的目标是促进创新的多学科研究， 流动性、平衡和老化。P/ESC管理晋升、申请、审查、奖励和 监测试点/探索性研究和开发项目。奖励的优先事项包括相关性 OAIC主题，独立资助的潜力，新的多学科合作和翻译 潜力发展项目的其他优先事项是有可能推进研究方法， 流动性、平衡性和老龄化领域，创新程度和纳入OAIC未来的潜力 问题研究为了最有效地利用资源， 鼓励研究。 拟议的第一年试点研究包括PES-1：NF-kB在干细胞衰老中的作用，PES-2：术前 电刺激治疗增强了老化肌肉的再生能力并恢复功能 术后活动度，PES-3，前屈肌松解症状机制的研究 老年脊柱狭窄患者和PES-4：行走的变异性、稳定性和平稳性。