Conference Series: From Bedside to Bench

描述(由申请者提供)：为了与最初的资助标题“床边到长凳”保持一致，我们强调会议的翻译方面，特别是使用临床问题来框架、定义和推动基本调查，并促进基础和临床研究人员之间的互动。这项建议延续了最初计划的许多成功特点；由老年病学界和NIA提供的意见开发的专题，有充足时间进行互动的多学科会议，来自传统老龄化研究社区内外的年轻研究人员、少数群体研究人员和知名领导人的参与，通过AGS年会的研讨会传播，通过美国老年医学学会杂志(JAGS)发表，以及其他媒体。根据AGS和NIA在过去一年制定的优先事项，我们提出了2007-2009年要解决的三个新主题：1)“思考、移动和感觉：衰老的认知、情绪和运动障碍是否有重叠的因果机制？”，2)“特发性衰老疲劳”，以及3)“炎症和营养代谢：作为有效干预的关键的相互作用。”这是代表美国老年医学学会(AGS)与美国国家老龄研究所(NIA)老年医学和临床老年学分会合作，申请为期三年的U13合作会议赠款。这一会议拨款计划的使命与最初的提议保持不变：“加强对临床上迫切关注的或有可能极大地改善老年人临床护理或预防的临床老年病问题的研究关注”。我们的长期目标仍然是“将研究成果转化为临床护理，以改善老年人的健康状况。”

DESCRIPTION (provided by applicant): In keeping with the original grant title "Bedside to Bench", we emphasize the translational aspect of the conferences, especially the use of clinical issues to frame, define and drive basic inquiry, and to promote interactions between basic and clinical investigators. This proposal continues many of the successful features of the original program; topics developed with input from the geriatrics community and the NIA, multidisciplinary conferences with ample time for interaction, participation by young investigators, minority investigators and established leaders from within and outside the traditional aging research community, dissemination through Symposia at the Annual Meeting of AGS and publication through the Journal of the American Geriatrics Society (JAGS), as well as other media. Based on priorities developed by AGS and NIA over the last year, we propose three new topics to be addressed in 2007-2009; 1) "Thinking, moving and feeling: do cognitive, mood and movement disorders of aging have overlapping causal mechanisms?", 2) "Idiopathic Fatigue of Aging," and 3) "Inflammation and nutrient metabolism: interaction as a key to effective intervention." This is an application for a three year U13 cooperative conference grant on behalf of the American Geriatrics Society (AGS) in cooperation with the Geriatrics and Clinical Gerontology branch of the National Institute on Aging (NIA). The mission of this conference grant program remains unchanged from the initial proposal; "to heighten research attention on clinical geriatrics issues that are of pressing concern clinically or have the potential to greatly improve clinical care or prevention for older adults". Our long term goal remains to "translate research results into clinical care that will improve the health outcomes of older adults."