OK COBRE: NUCLEIC ACID ANALYSIS CORE

OK COBRE：核酸分析核心

• 批准号: 7960576
• 负责人: KENNETH M KAUFMAN
• 金额: $ 65.76万
• 依托单位: OKLAHOMA MEDICAL RESEARCH FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-15 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7960576
• 关键词: Autoimmunity; Centers of Research Excellence; Computer Retrieval of Information on Scientific Projects Database; DNA Sequence; Data Analyses; Data Collection; Development; Equipment; Funding; Genetic; Genotype; Goals; Grant; Human Resources; Institution; Mentors; Molecular; Mus; Nucleic Acids; Research; Research Personnel; Resources; Services; Single Nucleotide Polymorphism; Source; Training; United States National Institutes of Health; assay development; design; experience; man; meetings; nucleotide metabolism; research study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of the Nucleic Acid Analysis Core is to provide COBRE investigators with resources and expertise to study molecular mechanisms at the nucleic acid level. To meet these goals, COBRE investigators are given access to specialized equipment, training and development, and design of experiments. The capabilities, assembled in the Nucleic Acid Analysis Core, provide the Junior Investigators a single point of entry, comprehensive advice (mentoring) for the technical aspects of experiments manipulating of nucleic acids, access to highly-trained technical personnel, and very sophisticated and expensive equipment. The Core will offer assay development, data collection, or nucleotide synthesis. This Core centralizes the equipment and experience needed to efficiently and reliably produce high quality nucleic acid analysis data. The services available through this Core include DNA sequencing, single nucleotide polymorphism (SNP) genotyping, expression arrays in mouse and man, and SNP arrays.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 核酸分析核心的目标是为Cobre研究人员提供资源和专业知识，以在核酸水平上研究分子机制。为了实现这些目标，Cobre的研究人员可以使用专门的设备、培训和开发以及实验设计。这些能力组装在核酸分析核心中，为初级调查人员提供了一个单一的切入点，为操纵核酸的实验的技术方面提供了全面的建议(指导)，获得了训练有素的技术人员，以及非常复杂和昂贵的设备。核心将提供分析开发、数据收集或核苷酸合成。这一核心集中了高效和可靠地产生高质量核酸分析数据所需的设备和经验。通过该核心提供的服务包括DNA测序、单核苷酸多态(SNP)基因分型、小鼠和人的表达阵列以及SNP阵列。