CORE B: NUCLEIC ACID ANALYSIS CORE

核心 B：核酸分析核心

• 批准号: 8359788
• 负责人: KENNETH M KAUFMAN
• 金额: $ 35.68万
• 依托单位: OKLAHOMA MEDICAL RESEARCH FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8359788
• 关键词: Autoimmunity; Centers of Research Excellence; DNA Sequence; Data Analyses; Data Collection; Development; Equipment; Funding; Genetic; Genotype; Goals; Grant; Human Resources; Mentors; Molecular; Mus; National Center for Research Resources; Nucleic Acids; Principal Investigator; Research; Research Infrastructure; Research Personnel; Resources; Services; Single Nucleotide Polymorphism; Source; Training; United States National Institutes of Health; assay development; cost; design; experience; man; meetings; nucleotide metabolism; research study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The goal of the Nucleic Acid Analysis Core is to provide COBRE investigators with resources and expertise to study molecular mechanisms at the nucleic acid level. To meet these goals, COBRE investigators are given access to specialized equipment, training and development, and design of experiments. The capabilities, assembled in the Nucleic Acid Analysis Core, provide the Junior Investigators a single point of entry, comprehensive advice (mentoring) for the technical aspects of experiments manipulating of nucleic acids, access to highly-trained technical personnel, and very sophisticated and expensive equipment. The Core will offer assay development, data collection, or nucleotide synthesis. This Core centralizes the equipment and experience needed to efficiently and reliably produce high quality nucleic acid analysis data. The services available through this Core include DNA sequencing, single nucleotide polymorphism (SNP) genotyping, expression arrays in mouse and man, and SNP arrays.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 核酸分析核心的目的是为毛cre研究者提供资源和专业知识，以研究核酸水平的分子机制。 为了实现这些目标，可以使毛绒调查人员使用专门的设备，培训和开发以及实验设计。 在核酸分析核心组装的功能为初级研究人员提供了一个单一的入学点，全面的建议（指导），用于操纵核酸的实验的技术方面，访问高度训练的技术人员以及非常精致且昂贵的设备。核心将提供测定开发，数据收集或核苷酸合成。该核心集中了有效，可靠地生成高质量核酸分析数据所需的设备和经验。通过此核心提供的服务包括DNA测序，单核苷酸多态性（SNP）基因分型，小鼠和人中的表达阵列以及SNP阵列。