SNP Confirmation and High Throughput Genotyping Core

在SNP确认和高重复性基因分型中组装的功能 核心（SNP-Gen核心）为中心研究者（和大型机构）提供单点 对实验的技术方面提供全面的咨询（指导） 操纵核酸，获得训练有素的技术人员， 复杂而昂贵的设备。对于大多数人来说，核心将提供检测开发， 数据收集或核苷酸合成。在某些情况下，建议和教育将是 得到了该核心集中了高效和高效地管理所需的设备和经验， 可靠地产生高质量的核酸分析数据。通过此提供的服务 核心包括DNA测序，单核苷酸多态性（SNP）基因分型， 插入/缺失分析、串联重复序列基因分型、小鼠中的表达阵列， 人和SNP阵列。适当的内部质量控制检查和平衡已经到位 并在修订后的申请中列出。与每个中心的互动 将对研究者进行量身定制，以满足每个人的个人培训需求。核心 用于高效且经济地提供数据和服务。在某些情况下 将产生大量高吞吐量数据。

The capabilities assembled in the SNP Confirmation and High Throughput Genotyping Core (SNP-Gen Core) provide the Center Investigators (and larger institution) a single point of entry, comprehensive advice (mentoring) for the technical aspects of experiments manipulating nucleic acids, access to highly-trained technical personnel and very sophisticated and expensive equipment. For most, the Core will offer assay development, data collection, or nucleotide synthesis. In some situations advice and education will be obtained. This Core centralizes the equipment and experience needed to efficiently and reliably produce high quality nucleic acid analysis data. The services available through this Core include DMA sequencing, single nucleotide polymorphism (SNP) genotyping, insertion/deletion analysis, tandem repeat genotyping, expression arrays in mouse and man, and SNP arrays. Appropriate internal quality control checks and balances are in place and are outlined in the revised application. The interaction with each of the Center Investigators will be tailored so that the individual training needs of each are met. The core serves to provide data and services efficiently and economically. In some situations massive high throughput data will be generated.