NEW DATA ANALYSIS METHODS FOR ACTIGRAPHY IN SLEEP MEDICINE

睡眠医学中体动描记法的新数据分析方法

• 批准号: 8071580
• 负责人: WILLIAM D. SHANNON
• 金额: $ 36.87万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8071580
• 关键词: Academy; Adolescent; Algorithms; American; Ankle; Area; Calibration; Child; Circadian Dysregulation; Circadian Rhythms; Clinical; Clinical Medicine; Clinical Research; Clinical assessments; Collection; Computer software; Data; Data Analyses; Dementia; Depressed mood; Development; Devices; Diagnosis; Diagnostic; Disease; Elderly; Emerging Technologies; Fatigue; Health; Imagery; Individual; Informatics; Israel; Link; Measures; Medical; Medicine; Methodology; Methods; Modeling; Movement; Neurology; Newborn Infant; Nursing Homes; Output; Patients; Pattern; Pharmaceutical Preparations; Polysomnography; Population; Printing; Process; Programming Languages; Recommendation; Recording of previous events; Recruitment Activity; Reporting; Research; Restless Legs Syndrome; Sampling; Schizophrenia; Severity of illness; Sleep; Sleep Apnea Syndromes; Sleep Disorders; Sleeplessness; Statistical Data Interpretation; Statistical Methods; Subgroup; Time; Universities; Washington; Wrist; actigraphy; clinically relevant; comparison group; data modeling; demographics; density; diaries; improved; interest; novel; open source; patient oriented; portability; programs; relational database; response; sleep abnormalities; statistics; tool; treatment response; volunteer

DESCRIPTION (provided by applicant): The purpose of this study to develop statistical and informatics tools for analyzing and visualizing actigraphy data linked to fatigue in sleep medicine center patients. An actigraph is a watch-like device attached to the wrist that uses an accelerometer to measure movement nearly continuously over several days. An American Academy of Sleep Medicine 2002 report defines the practice parameters for the use of actigraphy as a useful tool for detecting sleep in healthy individuals, assessing specific aspects in insomnia and restless leg syndrome, and a useful adjunct to a detailed history and subjective sleep diary for diagnosing and treating insomnia, circadian-rhythm disorders, and excessive sleepiness. Concurrent with these recommendations is an increased interest in the use of actigraphy as a tool for objectively measuring fatigue. With improved high-end statistical methods for analyzing this data, actigraphy has the potential to become more important as an objective diagnostic tool for determining fatigue, sleep abnormalities and assessing response to treatment. Other special areas of neurology and medicine where actigraphy can be used more effectively include restless leg syndrome, the elderly and nursing home patients with and without dementia, newborns, infants, children, and adolescents, hypertensive individuals, depressed or schizophrenic patients, and individuals in inaccessible situations. PUBLIC HEALTH RELEVANCE: With improved high-end statistical methods for analyzing actigraphy data, actigraphy has the potential to become more important in clinical medicine and research as an objective diagnostic tool for determining fatigue, sleep abnormalities and assessing response to treatment. Other special areas of neurology and medicine where actigraphy can be used more effectively include restless leg syndrome, the elderly and nursing home patients with and without dementia, newborns, infants, children, and adolescents, hypertensive individuals, depressed or schizophrenic patients, and individuals in inaccessible situations.

描述（由申请人提供）：本研究的目的是开发统计和信息学工具，用于分析和可视化与睡眠医学中心患者疲劳相关的活动图数据。活动记录仪是一种戴在手腕上的类似手表的设备，它使用加速度计在几天内几乎连续地测量运动。美国睡眠医学学会2002年的一份报告定义了使用活动描记术的实践参数，将其作为一种有用的工具，用于检测健康个体的睡眠，评估失眠和不宁腿综合征的具体方面，并且是诊断和治疗失眠、昼夜节律紊乱和过度嗜睡的详细历史和主观睡眠日记的有用辅助。在这些建议的同时，人们对使用活动描记术作为客观测量疲劳的工具越来越感兴趣。随着分析这些数据的高端统计方法的改进，活动记录仪有可能成为一种更重要的客观诊断工具，用于确定疲劳、睡眠异常和评估对治疗的反应。在神经病学和医学的其他特殊领域，活动记录仪可以更有效地使用，包括不动腿综合征，老年人和养老院患有或不患有痴呆症的患者，新生儿，婴儿，儿童和青少年，高血压患者，抑郁症或精神分裂症患者，以及在难以进入的情况下的个体。公共卫生相关性：随着分析活动图数据的高端统计方法的改进，活动图作为确定疲劳、睡眠异常和评估治疗反应的客观诊断工具，在临床医学和研究中有可能变得更加重要。在神经病学和医学的其他特殊领域，活动记录仪可以更有效地使用，包括不动腿综合征，老年人和养老院患有或不患有痴呆症的患者，新生儿，婴儿，儿童和青少年，高血压患者，抑郁症或精神分裂症患者，以及在难以进入的情况下的个体。

项目成果

Age-related effects on circadian phase in the sleep of patients with depression and insomnia.

年龄相关的抑郁症和失眠患者睡眠昼夜节律阶段的影响。

• DOI: 10.1080/15402002.2013.855213
• 发表时间: 2015
• 期刊: Behavioral sleep medicine
• 影响因子: 3.1
• 作者: Xian,Hong;Gonzalez,Carlos;Deych,Elena;Farris,Suzan;Ding,Jimin;Shannon,William;McCall,WVaughn
• 通讯作者: McCall,WVaughn

Phenotyping apathy in individuals with Alzheimer disease using functional principal component analysis.

使用功能主成分分析对阿尔茨海默病患者的冷漠表型进行分析。

• DOI: 10.1016/j.jagp.2012.12.012
• 发表时间: 2013
• 期刊: The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
• 作者: Zeitzer,JamieM;David,Renaud;Friedman,Leah;Mulin,Emmanuel;Garcia,Rene;Wang,Jia;Yesavage,JeromeA;Robert,PhilippeH;Shannon,William
• 通讯作者: Shannon,William