Immune tolerance in experimental autoimmune encephalomyelitis following transplant of bone marrow cells genetically encoding autoantigen

编码自身抗原的骨髓细胞移植后实验性自身免疫性脑脊髓炎的免疫耐受

• 批准号: nhmrc : 1004837
• 负责人: A/Pr Frank Alderuccio
• 金额: $ 22.61万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/immune-tolerance-experimental-encoding-autoantigen/109072
• 关键词: Immune; tolerance; experimental; autoimmune; encephalomyelitis

Autoimmune diseases affect 5-6% of the population and include diseases such as multiple sclerosis. Our studies focus on examining a gene therapy approach together with bone marrow transplantation to treating autoimmune diseases. Using a model for multiple sclerosis we are finding promising results

自身免疫性疾病影响5-6%的人口，包括多发性硬化症等疾病。我们的研究集中在检查基因治疗方法与骨髓移植一起治疗自身免疫性疾病。使用多发性硬化症的模型，我们发现了有希望的结果