Community Clinical Oncology Program: FL Pediatric CCOP

描述（由申请人提供）：佛罗里达儿科社区临床肿瘤项目是一个由佛罗里达州六家医院和波多黎各一家医院组成的联盟。这是美国运行时间最长的儿科CCOP。CCOP自1983年以来一直得到资助，其研究基地包括儿童肿瘤小组（COG）和H. Lee Moffitt癌症中心CCOP研究基地。在这26年期间，它是COG治疗和癌症控制研究中最大的患者贡献者之一。CCOP始终具有出色的遵从性得分，并通过其主持或共同主持研究基地协议的成员为COG的管理和科学做出贡献。CCOP在地理上覆盖了整个佛罗里达州，并为佛罗里达州最大的人口中心（美国第四大州）提供儿科肿瘤护理：奥兰多、坦帕、迈尔斯堡和佛罗里达州好莱坞。波多黎各的CCOP医院为整个岛屿和邻近的加勒比岛屿提供服务，是研究中少数民族患者的主要提供者。佛罗里达州儿科CCOP的目标是通过参与临床试验，为佛罗里达州和波多黎各的患者提供最新的癌症治疗进展，并为大多数符合条件的患者注册COG协议，从而在患者的家庭社区提供高质量的护理。莫菲特CCOP研究基地提高了癌症预防和控制研究的可用性。CCOP提供了一个独特的机会来研究地理上定义的人群，以调查危险因素、护理模式和基于人群的干预措施。佛罗里达州儿科CCOP还维护CCOP患者日志，这为确保大多数符合条件的患者在适当的COG协议上注册提供了机会。预计每年有超过194名患者注册COG治疗方案，每年有38名患者注册通过佛罗里达州7个儿科CCOP参与中心批准的癌症控制积分方案。COG和Moffitt质量控制程序统一适用于佛罗里达儿科CCOP，确保符合协议和病理，放疗，手术和化疗的外部审查。

DESCRIPTION (provided by applicant): The Florida Pediatric Community Clinical Oncology Program is a consortium of six Florida hospitals and one hospital in Puerto Rico. It is the longest functioning exclusively pediatric CCOP in the US. The CCOP has been continuously funded since 1983 and has the Children's Oncology Group (COG) and the H. Lee Moffitt Cancer Center CCOP Research Base as its research bases. It is among the single largest contributor of patients to treatment and cancer control studies in COG over this 26 year period. The CCOP consistently has outstanding compliance scores and contributes to the administration and science of COG through its members who chair or co-chair research base protocols. The CCOP geographically covers the entire state of Florida and provides pediatric oncology care to the largest population centers in Florida, the fourth largest state in the country: Orlando, Tampa, Ft. Myers, and Hollywood Florida. The CCOP hospital in Puerto Rico services the entire island and the neighboring Caribbean islands and is the major contributor of minority patients to studies. The goal of the Florida Pediatric CCOP is to make available the latest advances in cancer care to patients in Florida and Puerto Rico through participation in clinical trials and to register the majority of their eligible patients on COG protocols, thereby providing quality care in patients' home communities. The Moffitt CCOP Research Base enhances the availability of cancer prevention and control studies. The CCOP provides a unique opportunity to study a geographically-defined population to investigate risk factors, patterns of care, and population-based interventions. The Florida Pediatric CCOP also maintains the CCOP Patient Log which affords the opportunity to ensure the majority of eligible patients are registered on appropriate COG protocols. Over 194 patient registrations are anticipated per year on COG treatment protocols and 38 on protocols approved for cancer control credits per year through the 7 Florida Pediatric CCOP participating centers. COG and Moffitt quality- control procedures apply uniformly to the Florida Pediatric CCOP, ensuring compliance with protocols and external review of pathology, radiotherapy, surgery, and chemotherapy. RELEVANCE: The CCOP is the only mechanism for the majority of childhood cancer health care providers and cases in Florida and Puerto Rico to access cooperative group treatment and cancer control studies. It provides access to protocols, investigational drugs, quality assurance review and an opportunity to participate in cutting edge research that is not available otherwise in a community setting.