GENETIC AND TRAUMA-RELATED RISK FACTORS FOR PTSD

创伤后应激障碍的遗传和创伤相关风险因素

• 批准号: 8172379
• 负责人: KERRY J. RESSLER
• 金额: $ 3.29万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8172379
• 关键词: Adult; Biological; Communities; Computer Retrieval of Information on Scientific Projects Database; DNA; Disease; Education; Environmental Risk Factor; Funding; Genetic; Grant; Impulsivity; Institution; Interview; Measures; Neighborhoods; Physiological; Post-Traumatic Stress Disorders; Reporting; Research; Research Personnel; Resources; Risk; Risk Factors; Sampling; Source; Trauma; United States National Institutes of Health; pediatric trauma

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objective of this project is to identify environmental risk factors associated with PTSD; the interaction between childhood trauma, adult trauma exposure and risk for PTSD as an adult; other factors including neighborhood and community disorder, impulsivity, attachment variables and education and IQ are associated with increased risk of PTSD. During the 2009 reporting period, we were successful with recruitment demonstrating full feasibility for the project as a whole. Since June, we completed over 500 detailed interviews with full biological and physiological measures as well as collecting DNA samples and assessment interviews on over 2500 subjects.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 该项目的目的是确定与PTSD相关的环境风险因素； 童年创伤，成人创伤和成年PTSD风险之间的相互作用；其他因素，包括邻里和社区障碍，冲动性，依恋变量以及教育以及智商的其他因素与PTSD风险增加有关。 在2009年的报告期间，我们成功地招聘证明了整个项目的完全可行性。 自6月以来，我们完成了500多次详细访谈，并采用了全面的生理和生理措施，并收集了2500多名受试者的DNA样本和评估访谈。