HEMISPHERIC SPECIALIZATION AND COMMUNICATION

半球专业化和沟通

• 批准号: 8172323
• 负责人: WILLIAM D HOPKINS
• 金额: $ 4.39万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8172323
• 关键词: Brodmann' s area; Cerebral Dominance; Communication; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Handedness; Homologous Gene; Institution; Laboratories; Magnetic Resonance Imaging; Manuals; Measures; Pan Genus; Population; Research; Research Personnel; Resources; Role; Source; United States National Institutes of Health; Variant; Wernicke Area; in vivo

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This year, studies in our laboratory focused on the in vivo and post-mortem analysis of the volume and lateralization of the planum temporale (PT) (the homolog to Wernicke's area) in chimpanzees. We found that the PT as measured from magnetic resonance images corresponds well to the cytoarchitectural distribution of Brodmann's area 22 (BA22). At both the gross anatomical and cellular levels of analysis, significant population-level leftward asymmetries were found in the chimpanzees. We further found that variation in asymmetries in the PT were associated with handedness for gestural communication but not other manual actions, suggesting that it has a functional role in communication.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 今年，我们实验室的研究重点是对黑猩猩颞平面 (PT)（与韦尼克区同源）的体积和侧化进行体内和死后分析。 我们发现从磁共振图像测量的 PT 与布罗德曼区 22 (BA22) 的细胞结构分布很好地对应。 在总体解剖学和细胞水平的分析中，在黑猩猩中发现了显着的群体水平的左向不对称性。我们进一步发现，PT 不对称的变化与手势交流的惯用手有关，但与其他手动动作无关，这表明它在交流中具有功能性作用。