HEMISPHERIC SPECIALIZATION AND COMMUNICATION
HEMISPHERIC SPECIALIZATION AND COMMUNICATION
批准号:
8172323
负责人:
WILLIAM D HOPKINS
金额:
$4.39万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-05-01 至 2011-04-30
关键词:
Brodmann&aposs areaCerebral DominanceCommunicationComputer Retrieval of Information on Scientific Projects DatabaseFundingGrantHandednessHomologous GeneInstitutionLaboratoriesMagnetic Resonance ImagingManualsMeasuresPan GenusPopulationResearchResearch PersonnelResourcesRoleSourceUnited States National Institutes of HealthVariantWernicke Areain vivo
中文摘要
该子项目是利用该技术的众多研究子项目之一
资源由 NIH/NCRR 资助的中心拨款提供。子项目及
研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金,
因此可以在其他 CRISP 条目中表示。列出的机构是
对于中心来说,它不一定是研究者的机构。
今年,我们实验室的研究重点是对黑猩猩颞平面 (PT)(与韦尼克区同源)的体积和侧化进行体内和死后分析。 我们发现从磁共振图像测量的 PT 与布罗德曼区 22 (BA22) 的细胞结构分布很好地对应。
在总体解剖学和细胞水平的分析中,在黑猩猩中发现了显着的群体水平的左向不对称性。我们进一步发现,PT 不对称性的变化与手势交流的惯用手相关,但与其他手动动作无关,这表明它在交流中具有功能性作用。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
This year, studies in our laboratory focused on the in vivo and post-mortem analysis of the volume and lateralization of the planum temporale (PT) (the homolog to Wernicke's area) in chimpanzees. We found that the PT as measured from magnetic resonance images corresponds well to the cytoarchitectural distribution of Brodmann's area 22 (BA22).
At both the gross anatomical and cellular levels of analysis, significant population-level leftward asymmetries were found in the chimpanzees. We further found that variation in asymmetries in the PT were associated with handedness for gestural communication but not other manual actions, suggesting that it has a functional role in communication.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Genetic determinants of early brain development in an animal model of autism spectrum disorder (ASD)
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批准号:10376837
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项目类别:
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资助金额:$20.25万
-
财政年份:2021
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负责人:WILLIAM D HOPKINS
-
依托单位:
A Squirrel Monkey Model of Alzheimer’s Disease: Developing Behavioral, Blood, and CSF Biomarkers
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批准号:10284696
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项目类别:
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资助金额:$41.48万
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财政年份:2021
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负责人:WILLIAM D HOPKINS
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依托单位:
Alzheimer's Disease Pathology in a Primate Model
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批准号:10551282
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项目类别:
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资助金额:$74.62万
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财政年份:2021
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负责人:WILLIAM D HOPKINS
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依托单位:
Genetic determinants of early brain development in an animal model of autism spectrum disorder (ASD)
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批准号:10215682
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项目类别:
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资助金额:$24.3万
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财政年份:2021
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负责人:WILLIAM D HOPKINS
-
依托单位:
Alzheimer's Disease Pathology in a Primate Model
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批准号:10350661
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项目类别:
-
资助金额:$74.62万
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财政年份:2021
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负责人:WILLIAM D HOPKINS
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依托单位:
Specific Pathogen Free 18 Baboon Research Resource (SPF18BRR)
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批准号:10627136
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项目类别:
-
资助金额:$127.46万
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财政年份:2017
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负责人:WILLIAM D HOPKINS
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依托单位:
Specific Pathogen Free 18 Baboon Research Resource (SPF18BRR)
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批准号:10912917
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项目类别:
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资助金额:$27.01万
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财政年份:2017
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负责人:WILLIAM D HOPKINS
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依托单位:
HEMISPHERIC SPECIALIZATION AND COMMUNICATION
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批准号:8357394
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项目类别:
-
资助金额:$3.29万
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财政年份:2011
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负责人:WILLIAM D HOPKINS
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依托单位:
Vasopressin Receptor Polymorphism and Social Cognition
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批准号:8471263
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项目类别:
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资助金额:$39.52万
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财政年份:2011
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负责人:WILLIAM D HOPKINS
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依托单位:
Vasopressin Receptor Polymorphism and Social Cognition
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批准号:8517818
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项目类别:
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资助金额:$31.01万
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财政年份:2011
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负责人:WILLIAM D HOPKINS
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依托单位:
Heritability of Neuroanatomical Asymmetries in Primates
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批准号:8322577
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项目类别:
-
资助金额:$32.17万
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财政年份:2011
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负责人:WILLIAM D HOPKINS
-
依托单位:
Heritability of Neuroanatomical Asymmetries in Primates
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批准号:8534828
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项目类别:
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资助金额:$28.98万
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财政年份:2011
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负责人:WILLIAM D HOPKINS
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依托单位:
Heritability of Neuroanatomical Asymmetries in Primates
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批准号:8464458
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项目类别:
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资助金额:$5.38万
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财政年份:2011
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负责人:WILLIAM D HOPKINS
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依托单位:
Heritability of Neuroanatomical Asymmetries in Primates
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批准号:8239089
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项目类别:
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资助金额:$21.96万
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财政年份:2011
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负责人:WILLIAM D HOPKINS
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依托单位:
Heritability of Neuroanatomical Asymmetries in Primates
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批准号:8725748
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项目类别:
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资助金额:$29.94万
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财政年份:2011
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负责人:WILLIAM D HOPKINS
-
依托单位:
Vasopressin Receptor Polymorphism and Social Cognition
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批准号:8186229
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项目类别:
-
资助金额:$37.3万
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财政年份:2011
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负责人:WILLIAM D HOPKINS
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依托单位:
Neural Correlates of Language and Communication in Apes
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批准号:8059887
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项目类别:
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资助金额:$2.22万
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财政年份:2010
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负责人:WILLIAM D HOPKINS
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依托单位:
NEUROBIOLOGY OF HEMISPHERIC SPECIALIZATION IN PRIMATES
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批准号:7958109
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项目类别:
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资助金额:$4.39万
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财政年份:2009
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负责人:WILLIAM D HOPKINS
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依托单位:
Neural Correlates of Language and Communication in Apes
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批准号:7846323
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项目类别:
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资助金额:$2.4万
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财政年份:2009
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负责人:WILLIAM D HOPKINS
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依托单位:
Neuroanatomical Correlated of Cognitive Control
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批准号:7813297
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项目类别:
-
资助金额:$11.16万
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财政年份:2009
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负责人:WILLIAM D HOPKINS
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依托单位: