Effects of Sleep enhancement on affectve functioning

这个项目的主要目标是检查改善睡眠的短期和长期影响，作为一种 治疗青少年焦虑症的重要组成部分。这些目标建立在四条证据的基础上 关于青春期的睡眠和情绪调节：1)睡眠、昼夜节律和 青春期的情感系统增加了睡眠和情绪问题的脆弱性(和 他们的相互作用)，导致青春期睡眠困难的高比率。2)青春期 广泛性焦虑症特别容易出现睡眠问题，因为人们提高了警觉性和 睡前焦虑和沉思的倾向；3)睡眠不足会干扰情绪调节和苦恼 容忍，因此，睡眠困难在情感和社会领域造成了额外的负担 功能正常。4)失眠和慢性睡眠障碍是糖尿病发生的重要危险因素 抑郁和其他不利的健康后果。总而言之，这四条证据提出了 关于早期干预改善和提高睡眠质量的机会的引人注目的问题 带着焦虑的青春。项目2通过以下方式解决这些问题：(A)评估CBT期间的睡眠变化 焦虑，以检查睡眠改善是否可能部分调节CBT的一些积极效果；(B) 为CBT后继续表现出睡眠困难的儿童提供为期六周的睡眠干预(C) 通过随机化2/3接受多成分睡眠干预和1/3来测试这种睡眠干预 接受对比支持性治疗；以及(D)评估改善睡眠是否会进一步 增强情感、临床和社交功能。这个项目解决了一系列相当重要的问题 治疗焦虑症的临床意义。它还考察了青春期早期作为 开发睡眠干预的方法，为抑郁症的预防策略提供信息。更多 总的来说，这个项目涉及公共卫生和社会政策非常关注的问题，涉及 青年睡眠不足的后果不仅对认知、情绪、行为和 学术功能，但也有更广泛的健康问题，其中涉及睡眠，包括 情感障碍、酒精、尼古丁和其他物质的使用、事故和肥胖的发展 和代谢综合症。

The primary goals of this project are to examine the short and long-term effects of improving sleep as an important component of treating anxiety disorders in youth. These goals build upon four lines of evidence regarding sleep and emotion regulation in adolescence: 1) Developmental changes in sleep, circadian, and affective systems at puberty create increased vulnerabilities for both sleep and emotional problems (and their interactions) in ways that lead to high rates of sleep difficulties in adolescence. 2) Youth with Generalized Anxiety Disorder are particularly prone to sleep problems because of increased vigilance and inclinations to worry and ruminate at bedtime; 3) Sleep loss can interfere with affect regulation and distress tolerance, and thus, sleep difficulties create added burdens in the domains of affective and social functioning. 4) Insomnia and chronic sleep disturbance are significant risk factors for the development of depression and other adverse health outcomes. Taken together, these four lines of evidence raise compelling questions regarding the opportunities for early intervention to improve and enhance sleep in youth with anxiety. Project 2 addresses these questions by: (a) assessing sleep changes during CBT for anxiety to examine whether sleep improvements may partially mediate some positive effects of CBT; (b) offering a six-week sleep intervention to those children who continue to show sleep difficulties after CBT (c) testing this sleep intervention by randomizing 2/3 to receive the multi-component sleep intervention and 1/3 to receive a comparison supportive treatment; and (d) assessing whether improving sleep will further enhance affective, clinical, and social functioning. This project addresses a set of issues of considerable clinical relevance in treating anxiety disorders. It also examines early adolescence as a key time in development for sleep intervention in ways that could inform a prevention strategy for depression. More generally, this project addresses issues of great concern to public health and social policy regarding the consequences of insufficient sleep in youth¿not only its effects on cognitive, emotional, behavioral, and academic function, but also a broader range of health problems where sleep has been implicated, including the development of affective disorders, alcohol, nicotine, and other substance use, accidents, and obesity and metabolic syndrome.