K24 Clinical Research in Antimicrobial Resistance and Hospital Epidemiology

描述（由申请人提供）：这是一个为期五年的K24中期职业发展奖，旨在为Anthony Harris MD， MPH提供面向患者的研究和指导。该建议涉及在抗微生物药物耐药性和医院流行病学领域进行研究和指导。目前，他是一个NIH R01和一个CDC R01的首席研究员。在他担任教职的八年中，他发表了70多篇手稿。他指导了许多流行病学博士生和传染病研究员取得了成功的学术生涯，并获得了美国卫生保健流行病学学会的指导奖。他在抗菌素耐药性和医院流行病学领域的工作得到国际公认。Harris博士要求将该奖项的50%时间用于指导，在感染控制干预措施领域编写新的拨款，旨在减少抗菌素耐药性和医院感染的出现，并参加临床试验和随机聚类设计的课程，以改进其以患者为导向的研究。该奖项将使他减少他的行政和临床责任，为指导和研究提供更多的保护时间。这个奖项将帮助他实现他的长期目标，包括：1)降低医院感染的发生率，减少抗菌素耐药性的出现2)继续在抗菌素耐药性和医院流行病学领域成功获得NIH R01资助3)继续将他的以患者为导向的研究转向干预试验，包括随机集群干预试验4)继续发展他的指导技能，指导学员成功地追求学术临床研究事业。

DESCRIPTION (provided by applicant): This proposal is for a five year K24 Mid-Career Development Award for patient-oriented research and mentoring for Anthony Harris MD, MPH. The proposal involves research and mentoring in the areas of antimicrobial resistance and hospital epidemiology. At present, he is the principal investigator on one NIH R01 and one CDC R01. During his eight years as a faculty member, he has published more than 70 manuscripts. He has mentored a number of PhD epidemiology students and infectious disease fellows to successful academic careers and has received a mentoring award from the Society of Healthcare Epidemiology of America. He is internationally recognized for his work in the areas of antimicrobial resistance and hospital epidemiology. Dr. Harris is requesting this award to dedicate 50% of his time to mentoring, writing new grants in the areas of infection control interventions aimed at decreasing the emergence of antimicrobial resistance and nosocomial infections, and taking coursework in clinical trials and randomized-cluster design that will improve his patient-oriented research. This award will allow him to decrease his administrative and clinical responsibilities to allow more protected time for mentoring and research. This award will help him achieve his long-term goals, which include: 1) decreasing the incidence of nosocomial infections and decrease the emergence of antimicrobial resistance 2) continuing to successfully obtain NIH R01 funding in the areas of antimicrobial resistance and hospital epidemiology 3) continuing to move his patient-oriented research towards intervention trials including randomized-cluster intervention trials 4) continuing to develop his mentoring skills to mentor trainees to successfully pursue academic clinical research careers.