Supporting New Faculty Recruitment Through Biomedical Research Core Center

描述（由申请人提供）：响应RFA-OD-09-005，肯塔基大学（英国）P30申请的战略计划是为招募2名初级研究员提供支持，他们将沉浸在一个高度协作，跨学科的研究小组中，专注于胃肠道（Gl）癌症的诊断，预防和治疗。这个多产的小组由基础和临床科学家组成，包括分子和细胞生物学家、临床科学家（外科医生、胃肠病学家和医学肿瘤学家）、Gl病理学家、流行病学家、生物统计学家和药学院的研究人员，他们在药物设计和递送方面取得了成功。该计划的目的是支持有前途的初级研究人员，他们将参与转化Gl癌症研究项目，作为我们最近资助的P20项目（P20 CA127004）的一部分，该项目为全额资助的P50 Gl癌症SPORE应用程序的开发提供支持。我们的目标是培养未来的Gl癌症研究骨干，他们可以参与分子生物学，药物发现和临床护理的交叉，成为综合和团队方法的领导者，以了解Gl癌症的复杂问题，因为它与潜在的预防和治疗策略有关。该提案建立在马基癌症中心的势头和现有优势的基础上，并得到了大量机构、州和慈善机构的进一步支持。

DESCRIPTION (Provided by the applicant): The strategic plan of the University of Kentucky (UK) P30 application in response to RFA-OD-09-005 is to provide support for the recruitment of 2 junior investigators who will be immersed into a highly collaborative, interdisciplinary group of investigators focused on the diagnosis, prevention and treatment of gastrointestinal (Gl) cancers. This productive group consists of basic and clinical scientists, including molecular and cell biologists, clinician-scientists (surgeons, gastroenterologists, and medical oncologists), Gl pathologists, epidemiologists, biostatisticians and investigators in the School of Pharmacy with successful programs in drug design and delivery. The purpose of this program is to support promising junior investigators who will participate in translational Gl cancer research projects as part of our recently-funded P20 program (P20 CA127004) which provides support for the development of a fully-funded P50 Gl cancer SPORE application. Our goal is to develop a cadre of future Gl cancer investigators who can participate at the intersection of molecular biology, drug discovery and clinical care to become leaders in integrative and team approaches to understand the complex issues of Gl cancer as it relates to potential prevention and treatment strategies. This proposal builds upon the momentum and existing strengths at the Markey Cancer Center and is further supported by substantial institutional, state and philanthropic support.