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中文摘要
翻译
描述(由申请人提供):肯塔基州(英国)大学P30申请响应RFA-OD-09-005的战略计划是为招募2名初级研究者提供支持,这些研究者将参与高度协作的跨学科研究者小组,重点关注胃肠道(GI)癌症的诊断、预防和治疗。这个富有成效的小组由基础和临床科学家组成,包括分子和细胞生物学家,临床科学家(外科医生,胃肠病学家和医学肿瘤学家),GI病理学家,流行病学家,生物统计学家和药学院的研究人员,他们在药物设计和交付方面取得了成功。该计划的目的是支持有前途的初级研究人员,他们将参与翻译GI癌症研究项目,作为我们最近资助的P20计划(P20 CA 127004)的一部分,该计划为开发全额资助的P50 GI癌症SPORE应用提供支持。我们的目标是培养一批未来GI癌症研究人员,他们可以参与分子生物学、药物发现和临床护理的交叉领域,成为综合和团队方法的领导者,以了解GI癌症的复杂问题,因为它涉及潜在的预防和治疗策略。该提案建立在马基癌症中心的势头和现有优势的基础上,并得到了大量机构,国家和慈善机构的支持。
英文摘要
DESCRIPTION (Provided by the applicant): The strategic plan of the University of Kentucky (UK) P30 application in response to RFA-OD-09-005 is to provide support for the recruitment of 2 junior investigators who will be immersed into a highly collaborative, interdisciplinary group of investigators focused on the diagnosis, prevention and treatment of gastrointestinal (Gl) cancers. This productive group consists of basic and clinical scientists, including molecular and cell biologists, clinician-scientists (surgeons, gastroenterologists, and medical oncologists), Gl pathologists, epidemiologists, biostatisticians and investigators in the School of Pharmacy with successful programs in drug design and delivery. The purpose of this program is to support promising junior investigators who will participate in translational Gl cancer research projects as part of our recently-funded P20 program (P20 CA127004) which provides support for the development of a fully-funded P50 Gl cancer SPORE application. Our goal is to develop a cadre of future Gl cancer investigators who can participate at the intersection of molecular biology, drug discovery and clinical care to become leaders in integrative and team approaches to understand the complex issues of Gl cancer as it relates to potential prevention and treatment strategies. This proposal builds upon the momentum and existing strengths at the Markey Cancer Center and is further supported by substantial institutional, state and philanthropic support.
期刊论文(2)
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会议论文
DOI: 10.3390/ijms131215755
发表时间: 2012-11-26
期刊: International journal of molecular sciences
影响因子: 5.6
作者: [Du J, Xu R]
通讯作者: Xu R
Targeting the Immunosuppressive Tumor Microenvironment for Colorectal Cancer Treatment
  • 批准号:
    10748123
  • 项目类别:
  • 资助金额:
    $40.03万
  • 财政年份:
    2023
  • 负责人:
    Bernard Mark Evers
  • 依托单位:
Appalachian Career Training in Oncology (ACTION) Program
  • 批准号:
    10001327
  • 项目类别:
  • 资助金额:
    $45.04万
  • 财政年份:
    2018
  • 负责人:
    Bernard Mark Evers
  • 依托单位:
Appalachian Career Training in Oncology (ACTION) Program
  • 批准号:
    10245140
  • 项目类别:
  • 资助金额:
    $45.98万
  • 财政年份:
    2018
  • 负责人:
    Bernard Mark Evers
  • 依托单位:
Appalachian Career Training in Oncology (ACTION) Program
  • 批准号:
    10475257
  • 项目类别:
  • 资助金额:
    $45.98万
  • 财政年份:
    2018
  • 负责人:
    Bernard Mark Evers
  • 依托单位:
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