Steering Undergraduate Interest in Environmental Health Sciences at the Universit

描述（由申请人提供） 北达科他州大学的STEER旨在支持北达科他州大学内环境健康科学的本科生培训。STEER培训计划将扩大和补充正在进行的NIH IDEA INBRE计划，该计划专注于在该州主要的本科院校培养本科生生物医学研究，并加强本科生到卫生专业学校的管道。北达科他州INBRE的重点是“健康和环境”。本申请旨在填补北达科他州INBRE计划不提供的环境科学本科生培训的重要空白。这一差距是对INBRE主办研究密集型机构北达科他州大学本科生环境科学培训的支持。本申请将利用INBRE基金会在北达科他州大学启动一个强大的环境健康科学本科生培训计划。研究主题将是推进这样一个假设，即引发人类疾病的环境因子会导致细胞结构和功能的细胞改变，这些改变可以被确定为疾病发展和进展的预测生物标志物。为了推进这一主题，学生将参与研究环境污染物砷和镉在人类膀胱，乳腺，前列腺和肾脏疾病的发展和进展中的作用的研究。该计划的目的是：在环境科学提供本科生的研究经验，本科生在北达科他州的大学;在北达科他州的大学本科生提供环境健康科学的介绍;并使用在INBRE计划开发的基础设施，以支持STEER方案的努力，反之亦然，在整个生命的奖励机制。

DESCRIPTION (provided by applicant) The University of North Dakota STEER is designed to support undergraduate training in the environmental health sciences within the University of North Dakota. The STEER training program will expand and compliment the ongoing NIH IDeA INBRE program that is focused on fostering undergraduate biomedical research at the State's primarily undergraduate institutions and the enhancement of the undergraduate pipeline to the health professional schools. The North Dakota INBRE is focused on "Health and the Environment". The present application is targeted at filling an important gap in undergraduate training in the environmental sciences not provided by the North Dakota INBRE program. This gap is the support of undergraduate environmental science training for undergraduate students at the INBRE host research-intensive institution, the University of North Dakota. The present application will use the INBRE foundation to initiate a strong undergraduate training program in environmental health science at the University of North Dakota. The research theme will be to advance the hypothesis that environmental agents which elicit human disease cause cellular alterations in cell structure and function that can be identified as predictive biomarkers of disease development and progression. To advance this theme, the students will be involved in research that studies the role of the environmental pollutants, arsenic and cadmium, in the development and progression of human bladder, breast, prostate, and renal disease. The aims of the program are: to provide an undergraduate research experience in environmental sciences to undergraduate students at the University of North Dakota; to provide an introduction to environmental health sciences to undergraduate students at the University of North Dakota; and, to use infrastructure developed in the INBRE program to support STEER programmatic efforts and vice versa over the life of the award mechanisms.