CTSA INFRASTRUCTURE FOR CLINICAL TRIALS

该子项目是对CTSA供资的百分比的估计， 用于广泛的研究领域（艾滋病研究，儿科研究，或 临床试验）。 列出的总成本仅为CTSA金额的估算 用于该研究领域的基础设施，而不是直接提供的资金 向子项目或子项目工作人员提供NCRR补助金。 威斯康星大学麦迪逊分校（UW）致力于转变其文化和教育的挑战，以发展临床和转化科学作为一个独特的学科。华盛顿大学以医学院正在进行的转型为医学和公共卫生学院提供的独特视角来应对这一挑战，该学院要求通过将其转化为当前实践，在有效应用现有知识的基础上创建一个健康服务系统。实现这一目标是由UW从其健康科学学校和马什菲尔德诊所建立的强大而坚定的伙伴关系中获得的力量。为了对UW的研究活动进行必要的重新设计，该大学成立了临床和转化研究所（ICTR），该研究所将作为实现临床和转化研究企业转型的工具。结合新资源的催化投资与现有资源的整合，协同作用和放大，该研究所将在研究工作中形成实质性的变化，并在UW的临床和转化研究的环境和文化中产生根本性的变化。卢旺达问题国际法庭的目标是创造一种环境，促进大学的研究转化为从调查到发现再到转化为实践的连续体。实现这一目标的主要重点是为临床和转化科学学科发展一个学术之家，这有利于创建和支持有效的跨学科研究团队。实现这一目标的关键是建立在临床研究培训计划的基础上，培养一批多学科的生物医学和行为科学家，他们能够加速将研究成果转化为基于证据的政策和实践，这将改善美国的健康状况。这些成果将通过为UW的研究人员提供现成的关键资源来促进，包括信息学工具，生物统计支持和核心技术。研究小组由此产生的创新发现将通过卢旺达问题国际法庭新的社区伙伴关系和通过威斯康星州广泛而发达的临床网络转化为保健实践。这些举措将成功地创造一个新的文化在UW，这将实现"威斯康星州的想法"，一个概念，在大学的努力联系到威斯康星州和社区以外的居民的福祉。

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The University of Wisconsin-Madison (UW) is committed to the challenge of transforming its culture and nvironment to develop clinical and translational science as a distinct discipline. UW approaches this challenge with the unique perspective afforded by the ongoing transformation of the Medical School to a School of Medicine and Public Health, which mandates creation of a health delivery system based on effective application of current knowledge by turning it into current practice. Achieving this goal is facilitated by the strength UW derives from a strong and committed partnership forged by its Health Science Schools and Marshfield Clinic. To undertake the necessary re-engineering of research activity at UW, the University formed the Institute for Clinical and Translational Research (ICTR), which will serve as the vehicle to achieve the transformation of the clinical and translational research enterprise. Coupling a catalytic investment of new resources with the integration, synergy and amplification of existing resources, the Institute will forge substantive changes in the research effort and effect fundamental change in the environment and culture for clinical and translational research at UW. The goal of the ICTR is to create an environment that facilitates transformation of research at the University into a continuum extending from investigation to discovery to translation into practice. The primary focus to achieve this end is development of an academic home for the discipline of clinical and translational science, which is conducive to the creation and support of effective interdisciplinary research teams. Essential to fulfillment of this objective is building upon clinical research training programs to develop a cadre of multidisciplinary biomedical and behavioral scientists capable of accelerating translation of research findings into evidence-based policies and practices, which will improve health in the United States. Such outcomes will be facilitated by providing investigators at UW readily available critical resources, including informatics tools, biostatistical support and core technologies. The resultant innovative discoveries of research teams will be translated to health practice via a novel ICTR community partnership and through an extensive well-developed clinical network in Wisconsin. These initiatives will successfully create a new culture at UW, which will fulfill the "Wisconsin Idea," a concept that links the efforts at the University to the well-being of the residents of Wisconsin and communities beyond.