CTSA INFRASTRUCTURE FOR AIDS RESEARCH

CTSA 艾滋病研究基础设施

• 批准号: 8365211
• 负责人: DAVID M. CENTER
• 金额: $ 21.06万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365211
• 关键词: Acquired Immunodeficiency Syndrome; Award; Boston; Clinical Sciences; Clinical and Translational Science Awards; Research; Research Infrastructure; Translational Research; Universities; programs

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. Boston University proposes to create a Clinical and Translational Science Institute, the BU-BRIDGE Institute, that will integrate, connect and expand our current research and university programs and, thereby, provide an academic and intellectual home for the next generation of clinical and translational investigators. The Institute will be organized around five Divisions: 1} Translational Science Incubator; 2) Informatics; 3) Clinical Research Enhancements; 4) Community Engagements; and 5) Research Education and Training. These five divisions are specifically designed to support the bi-directional development and translation of ideas that begin in the laboratory or bedside move seamlessly back and forth to result in new relevant tools to improve health, health care and delivery. The BU-BRIDGE will accomplish five specific aims: 1) Coordinate existing and identify new collaborations among existing BU scientists with the potential to develop into multidisciplinary translational programs, and facilitate the BU "one stop shopping" program for creating intellectual property and commercialization of translational scientific ideas; 2) Support the further development of existing and the creation of new translational programs and cores through a network of pilot grants. 3) Provide new and existing Clinical and Translational research programs with an expanded and enriched menu of BU-BRIDGE-based institutional support, including an improved, user friendly medical informatics syslem (warehouse), expansion of research from our GCRC into community populations, provide an integrated approach to ethics, regulatory issues, study design, analysis and implementation of health interventions 4) Provide the conduit for bi- directional flow of ideas between clinicians and clinical and basic scientists to more fully engage the community in the research process including setting priorities for investigation, designing studies, ensuring ethical research conduct and implementing best practices based on study results; 5) Serve as the Center for training the next generation of investigators with the proper tools to translate basic science into clinical research. The new institute is cross University entity that supercedes traditional departments and schools. It encorporates multiple key university programs including the National Emerging Infectious Diseases Laboratory, Framingham Heart Study, Boston University Office of Technology Development Commercialization portfolio, Departments of Biomedical Engineering and Bioinformatics, Sargent College of Allied Heath Professionals, the Boston Health Net, Boston Medical Center and VA Hospitals that support the university wide commitment for a home for translational research. The CTSA award will provide the resources to transform the institute by leveraging existing strengths to create an environment that will link new ideas, faculty, trainees and university programs to speed innovations in medical science. The mission of the BU-BRIDGE is relevant to the public health as it will enhance the development of healthcare practices available to members of the local and national communities.

该子项目代表了 CTSA 资金百分比的估计 被用于广泛的研究领域（艾滋病研究、儿科研究或 临床试验）。 列出的总成本只是 CTSA 金额的估计值 该研究领域的基础设施，而不是直接资助 NCRR 向子项目或子项目人员提供的补助金。 波士顿大学提议创建一个临床和转化科学研究所，即 BU-BRIDGE 研究所，该研究所将整合、连接和扩展我们当前的研究和大学项目，从而为下一代临床和转化研究人员提供学术和智力家园。该研究所将围绕五个部门进行组织： 1} 转化科学孵化器； 2）信息学； 3）临床研究的增强； 4）社区参与； 5) 研究教育和培训。这五个部门专门用于支持从实验室或床边开始的双向开发和思想转化，无缝地来回移动，以产生新的相关工具来改善健康、医疗保健和分娩。 BU-BRIDGE将实现五个具体目标：1）协调现有的BU科学家之间的现有合作并确定新的合作，这些科学家有潜力发展成多学科转化项目，并促进BU“一站式购物”项目创造知识产权和转化科学思想的商业化； 2) 通过试点资助网络，支持现有转化项目和核心的进一步发展以及新转化项目和核心的创建。 3) 提供新的和现有的临床和转化研究项目，以及基于 BU-BRIDGE 的机构支持的扩展和丰富菜单，包括改进的、用户友好的医疗信息系统（仓库），将研究从 GCRC 扩展到社区人群，提供伦理、监管问题、研究设计、分析和健康干预措施实施的综合方法 4) 为临床医生与临床和基础设施之间的双向思想流动提供渠道 科学家更充分地让社会参与研究过程，包括确定调查优先事项、设计研究、确保研究行为符合道德规范以及根据研究结果实施最佳实践； 5) 作为培训下一代研究人员的中心，使用适当的工具将基础科学转化为临床研究。新学院是跨大学实体，取代了传统的院系和学院。它包含多个重要的大学项目，包括国家新兴传染病实验室、弗雷明汉心脏研究、波士顿大学技术开发商业化组合办公室、生物医学工程和生物信息学系、萨金特联合健康专业人员学院、波士顿健康网、波士顿医疗中心和退伍军人管理局医院，支持大学对转化研究之家的广泛承诺。 CTSA 奖项将为研究所转型提供资源，利用现有优势创造一个将新想法、教师、学员和大学项目联系起来的环境，以加速医学科学的创新。 BU-BRIDGE 的使命与公共卫生相关，因为它将促进当地和国家社区成员可用的医疗保健实践的发展。