Boston University Clinical and Translational Science Institute - U Program

描述（由申请人提供）：波士顿大学临床和转化科学研究所（BU CTSI）由波士顿大学医学院（申请人），波士顿大学查尔斯河校区，波士顿医疗中心及其15个社区卫生中心和罗杰威廉姆斯医疗中心组成，位于罗德岛普罗维登斯，以及与波士顿VAMC和伊迪丝·诺斯·罗杰斯纪念退伍军人医院的合作伙伴关系。该研究所的愿景集中在提供资源和服务的过程改进，改变游戏规则的破坏性创新和基于能力的团队科学教育。三个高度互动的研究所目标是帮助创建最有效的临床和转化研究系统，开发创造性的科学工具来加快和重组传统的研究过程，并培训未来的转化科学家来做到这一点。我们将：1)创建一个转化科学的综合家园

DESCRIPTION (provided by applicant): The Boston University Clinical and Translational Science Institute (BU CTSI) is comprised of the BU Medical Campus (applicant), BU Charles River Campus, Boston Medical Center with its 15 Community Health Centers and Roger Williams Medical Center, in Providence, Rhode Island, along with partnerships with the Boston VAMC and Edith Norse Rogers Memorial Veterans Hospital. The Institute's vision centers on process improvement in providing resources and services, on game-changing disruptive innovations and on competency based team science education. Three highly interactive institute aims help create the most efficient system for clinical and translational research, develop creative scientific tools to expedite and retool traditional research processes, and train future translational scientists to do it. We will: 1) Create an Integrated Home for translational science that: A. integrates a pilot award program to target gaps in drug and device development; B. has a highly secure HIPAA compliant NIST-approved environment for data; C. contains efficiency measures for human subjects research; and D. incorporates new evaluation tools that assess processes and costs to be responsive to new opportunities and strategies. 2) Create an efficient delivery of Clinical and Translational Research Services to implement solutions that streamline and improve the quality, safety, efficiency and cost of clinical research. These include: A. skilld research personnel; B. an EMR-based Registry of ethnic populations; C. faster regulatory approval; D. consultative services for study design, biostatistics and bioinformatics; E. biobanking blood from our Registry for creation of iPS cells from normal subjects for drug toxicity screening; and F. creative tools to expedite and retool traditional research. 3) Create a Career Development Program for Future Scientists that: A. has a competency-based curriculum and evaluation approaches; B. supports a KL2 mentor based program in translational science; C. launches a new TL1 Program for supporting PhD scholars in translational science focused on regenerative medicine; D. provides mentor skill building tools to sustain high quality research mentoring; E. creates online self-directed modularized courses to enhance knowledge in informatics and other key translational research topics; F. implements an education evaluation plan and G. helps scientists with the downstream phase of commercialization of research. These associations and aims will support the mission of NCATS to change and speed the planning and implementation of clinical and translational research.