TREATMENT VERIFICATION AND TREATMENT PLAN REFINEMENT

治疗验证和治疗计划完善

• 批准号: 8102831
• 负责人: JAMES M BALTER
• 金额: $ 25.37万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8102831
• 关键词: Attention; Clinic; Clinical Research; Collection; Data; Data Collection; Evaluation; Feedback; Image; Link; Measures; Methodology; Modification; Monitor; Motion; Positioning Attribute; Process; Protocols documentation; Technology; Translating; Translations; programs; skills; tool; treatment planning

The clinical studies proposed in this program project application require a significant coordinated effort of technology translation with careful attention to data collection and analysis. The safe and effective implementation of new paradigms for treatment planning, in-room verification, and feedback tightly linked to treatment plan adjustment will require the combined efforts of a dedicated team of physicists, dosimetrists, and technologists. The careful collection of imaging data in a protocol setting will require onsite staff. The Core will provide the effort to support daily in-room imaging and monitoring of treatment. Through the combined skills of an integrated group of experts in the various components of the dynamic refinement process, we will be able to translate these concepts to the clinic and provide feedback for optimization and localization strategies. This core will be responsible for all aspects of the transition to the adaptive planning and treatment evaluation (including plan modification during treatment) process. Staff of the Core will assist in implementation of new localization, planning, and evaluation tools and methodologies in the clinic. Volumetric imaging data and related measures of position and motion will be collected by the Core staff for use by the projects and other cores.

该计划项目申请中提出的临床研究需要以下方面的重大协调努力： 技术翻译特别注重数据收集和分析。安全有效 实施紧密联系的治疗计划、室内验证和反馈的新范例 治疗计划的调整需要专门的物理学家团队的共同努力， 剂量测定师和技术人员。在协议设置中仔细收集成像数据将需要现场 职员。 核心将努力支持日常室内成像和治疗监测。通过 动态细化各个组成部分的综合专家组的综合技能 过程中，我们将能够将这些概念转化为临床，并提供反馈以进行优化和 本地化策略。该核心将负责向自适应规划过渡的各个方面 和治疗评估（包括治疗期间计划的修改）过程。核心工作人员将协助 在诊所实施新的本地化、规划和评估工具和方法。 体积成像数据以及相关的位置和运动测量将由核心工作人员收集以供使用 由项目和其他核心。