TREATMENT VERIFICATION AND TREATMENT PLAN REFINEMENT

在本计划项目申请中提出的临床研究需要显著的协调努力 认真注意数据收集和分析的技术翻译。安全有效的 实施治疗规划、室内核查和反馈密切相关的新模式 调整治疗计划将需要一支敬业的物理学家团队的共同努力， 剂量学家和技术专家。在协议设置中仔细收集成像数据将需要现场 工作人员。 该中心将努力支持日常的室内成像和治疗监测。通过 在动态细化的各个组件中综合专家小组的综合技能 过程中，我们将能够将这些概念转化为临床，并提供反馈以进行优化和 本地化战略。该核心将负责向适应性规划过渡的所有方面 和治疗评估(包括治疗过程中的计划修改)过程。中心的工作人员将提供协助 在临床上实施新的本地化、规划和评估工具和方法。 核心工作人员将收集体积成像数据以及位置和运动的相关测量数据以供使用 通过项目和其他核心。

The clinical studies proposed in this program project application require a significant coordinated effort of technology translation with careful attention to data collection and analysis. The safe and effective implementation of new paradigms for treatment planning, in-room verification, and feedback tightly linked to treatment plan adjustment will require the combined efforts of a dedicated team of physicists, dosimetrists, and technologists. The careful collection of imaging data in a protocol setting will require onsite staff. The Core will provide the effort to support daily in-room imaging and monitoring of treatment. Through the combined skills of an integrated group of experts in the various components of the dynamic refinement process, we will be able to translate these concepts to the clinic and provide feedback for optimization and localization strategies. This core will be responsible for all aspects of the transition to the adaptive planning and treatment evaluation (including plan modification during treatment) process. Staff of the Core will assist in implementation of new localization, planning, and evaluation tools and methodologies in the clinic. Volumetric imaging data and related measures of position and motion will be collected by the Core staff for use by the projects and other cores.