TREATMENT VERIFICATION AND TREATMENT PLAN REFINEMENT

本计划项目申请中提出的临床研究需要大量的协调努力， 技术翻译，并仔细注意数据收集和分析。安全有效 实施治疗计划、室内验证和反馈紧密联系的新范例 治疗计划的调整将需要一个专门的物理学家团队的共同努力， 放射量测定师和技术专家。在协议设置中仔细收集成像数据将需要现场 工作人员 核心将努力支持每日室内成像和治疗监测。通过 综合专家组在动态细化的各个组成部分的综合技能 过程中，我们将能够将这些概念转化为临床，并为优化和 本土化战略。该核心将负责向适应性规划过渡的所有方面 和治疗评估（包括治疗过程中的计划修改）过程。核心小组的工作人员将协助 在诊所实施新的本地化、规划和评估工具和方法。 核心工作人员将收集体积成像数据和位置和运动的相关测量值，以供使用 项目和其他核心。

The clinical studies proposed in this program project application require a significant coordinated effort of technology translation with careful attention to data collection and analysis. The safe and effective implementation of new paradigms for treatment planning, in-room verification, and feedback tightly linked to treatment plan adjustment will require the combined efforts of a dedicated team of physicists, dosimetrists, and technologists. The careful collection of imaging data in a protocol setting will require onsite staff. The Core will provide the effort to support daily in-room imaging and monitoring of treatment. Through the combined skills of an integrated group of experts in the various components of the dynamic refinement process, we will be able to translate these concepts to the clinic and provide feedback for optimization and localization strategies. This core will be responsible for all aspects of the transition to the adaptive planning and treatment evaluation (including plan modification during treatment) process. Staff of the Core will assist in implementation of new localization, planning, and evaluation tools and methodologies in the clinic. Volumetric imaging data and related measures of position and motion will be collected by the Core staff for use by the projects and other cores.