Frontal asymmetries and interpersonal anger, aggression, and inhibition across ad

广告中的额叶不对称和人际愤怒、攻击性和抑制

• 批准号: 8118072
• 负责人: Jill Malik
• 金额: $ 2.89万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-23 至 2012-11-22
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8118072
• 关键词: Adult; Affective; Age; Aggressive behavior; Anger; Behavioral; Behavioral inhibition; Borderline Personality Disorder; Brain; Child; Clinical; Clip; Cognitive; Coronary heart disease; Depressed mood; Development; Disease; Elderly; Electroencephalography; Emotional; Emotions; Family; Feeling; Film; Goals; Happiness; Hospitalization; Hostility; Individual; Intermittent Explosive Disorders; Intervention; Knowledge; Laboratories; Lead; Left; Life; Link; Longevity; Measures; Mediating; Mental disorders; Methods; Motivation; Neural Pathways; Neurologic; Neuropsychological Tests; Participant; Pathway interactions; Pattern; Performance; Physical aggression; Prefrontal Cortex; Prevention; Property; Psychophysiology; Relapse; Reporting; Research; Research Design; Right-On; Risk; Role; Simulate; Staging; Stimulus; Symptoms; System; Testing; Time; Translating; Translations; Withdrawal; analog; arm; emotional reaction; experience; frontal lobe; innovation; interest; neuromechanism; neuropsychological; partner aggression; pre-doctoral; programs; response; social; trait; young adult

There is growing evidence that left versus right prefrontal activation asymmetries support approach- and withdrawal-related emotions, respectively. Anger is associated with aggressive behavior and reduced inhibition, which has been shown to rely on the right prefrontal cortex. This proposal aims to explore the role of approach-related prefrontal activity in mediating the relationship between anger and behavioral inhibition. This will be accomplished by examining deficits in behavioral inhibition following anger induction as well as activity on a behavioral aggression task, as a function of both baseline and anger-induced asymmetries in prefrontal cortex activity. Lastly, lifespan considerations will be explored in respect to the mechanisms leading from anger to aggression, as research suggests a differential pattern of emotional responding later in life. This is a predoctoral proposal that will be the first step in a program of research designed to understand the neural mechanisms that lead from anger to aggression; the ultimate goal is to predict and mitigate anger-related changes in aggressive behavior.

越来越多的证据表明，左与右前额叶激活不对称分别支持接近和撤回相关的情绪。愤怒与攻击性行为和减少抑制有关，这已经被证明依赖于右前额叶皮层。本研究旨在探讨接近相关前额叶活动在愤怒与行为抑制之间的中介作用。这将通过检查愤怒诱导后行为抑制的缺陷以及行为攻击任务的活动来完成，作为基线和愤怒诱导的前额叶皮层活动不对称的函数。最后，将探讨从愤怒到攻击的机制方面的寿命考虑，因为研究表明，在以后的生活中，情绪反应有不同的模式。这是一个博士前的提议，将是一个研究计划的第一步，该计划旨在了解从愤怒到攻击的神经机制;最终目标是预测和减轻攻击行为中与愤怒相关的变化。