Social Determinants of the Autism Epidemic

自闭症流行的社会决定因素

• 批准号: 8119452
• 负责人: Peter Shawn Bearman
• 金额: $ 79.7万
• 依托单位: COLUMBIA UNIV NEW YORK MORNINGSIDE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-30 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8119452
• 关键词: Attention; Autistic Disorder; Automobile Driving; Complex; Data; Data Set; Diagnostic; Environment; Epidemic; Genes; Modeling; Prevalence; Social Network; United States; design; developmental disease; social

PS Bearman ¿ Social Determinants of the Autism Epidemic This project is designed to understand the rapid increase in autism prevalence in the United States over the past two decades. Proposed are new analyses of complex, multilevel temporally sensitive data sets that will enable me to determine the extent to which familial, environmental, gene-environment, and diagnostic drift/substitution are driving the autism epidemic. Detailed attention to and models capable of capturing social network and social influence underpinnings of the epidemic are developed. New analysis models for intercalating spatial and social network data are developed. These models where appropriate are extended to a wide range of developmental disorders that have increased rapidly in prevalence.

PS Bearman：自闭症流行的社会决定因素 该项目旨在了解自闭症患病率的快速增长， 美国在过去的二十年里。提出了新的分析复杂的，多层次的 时间敏感的数据集，使我能够确定在多大程度上， 家庭、环境、基因-环境和诊断漂移/替代是驱动因素 自闭症的流行详细的关注和模型能够捕捉社会 网络和社会影响力是这一流行病的基础。新 开发了用于插入空间和社会网络数据的分析模型。这些 模型在适当的情况下扩展到广泛的发育障碍， 在流行程度上迅速增加。

项目成果

Can Sibling Sex Ratios Be Used as a Valid Test for the Prenatal Androgen Hypothesis of Autism Spectrum Disorders?

兄弟姐妹性别比可以用作自闭症谱系障碍产前雄激素假说的有效测试吗？

• DOI: 10.1371/journal.pone.0141338
• 发表时间: 2015
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Cheslack-Postava,Keely;Susser,Ezra;Liu,Kayuet;Bearman,PeterS
• 通讯作者: Bearman,PeterS

Authors' response to: cohort effects explain the increase in autism diagnosis: an identifiability problem of the age-period-cohort model.

作者的回应：队列效应解释了自闭症诊断的增加：年龄-周期-队列模型的可识别性问题。

• DOI: 10.1093/ije/dyu214
• 发表时间: 2014
• 期刊: International journal of epidemiology
• 影响因子: 7.7
• 作者: Keyes,KatherineM;Susser,Ezra;Cheslack-Postava,Keely;Fountain,Christine;Liu,Kayuet;Bearman,PeterS
• 通讯作者: Bearman,PeterS

Reply: CDC analysis of ICSI/autism: association is not causation.

回复：CDC 对 ICSI/自闭症的分析：关联不是因果关系。

• DOI: 10.1093/humrep/dev107
• 发表时间: 2015
• 期刊: Human reproduction (Oxford, England)
• 作者: Kissin,DmitryM;Zhang,Yujia;Boulet,ShereeL;Fountain,Christine;Bearman,Peter;Schieve,Laura;Yeargin-Allsopp,Marshalyn;Jamieson,DeniseJ
• 通讯作者: Jamieson,DeniseJ

Age of diagnosis for autism: individual and community factors across 10 birth cohorts.

• DOI: 10.1136/jech.2009.104588
• 发表时间: 2011-06
• 期刊: Journal of epidemiology and community health
• 影响因子: 6.3
• 作者: Fountain C;King MD;Bearman PS
• 通讯作者: Bearman PS

Does Autism Diagnosis Age or Symptom Severity Differ Among Children According to Whether Assisted Reproductive Technology was Used to Achieve Pregnancy?

儿童自闭症诊断年龄或症状严重程度是否会因是否使用辅助生殖技术怀孕而有所不同？

• DOI: 10.1007/s10803-015-2462-1
• 发表时间: 2015
• 期刊: Journal of autism and developmental disorders
• 影响因子: 3.9
• 作者: Schieve,LauraA;Fountain,Christine;Boulet,ShereeL;Yeargin-Allsopp,Marshalyn;Kissin,DmitryM;Jamieson,DeniseJ;Rice,Catherine;Bearman,Peter
• 通讯作者: Bearman,Peter