A1B: MULTI-USER RESEARCH CORE FACILITIES- ANALYTICAL CORE LAB:ENVIRONMENTAL HLTH

近年来，分析核心实验室(ACL)为RCMI计划的成功做出了重大贡献。在目前的资助期内，该中心已为2个试点项目PIS(Hamme博士和Liu博士)和其他17名教职员工以及科学、工程和技术学院(CSET)的大量研究助理、技术人员和学生提供了分析服务。 这些ACL用户非常积极地发表同行评议论文(在过去5年中超过110篇)，并在同一时期在国内或国际会议上发表了200多篇论文。此外，使用ACL的教职员工目前正在接受二十二(22)项研究资助。为了进一步提高这些教师的工作效率，满足ACL用户对生物医学和环境健康研究的需求，提出了以下计划：(1)ACL将提供实验室 支持3个新的RCMI试点项目，并促进他们的PIS(Arslan、Gao和Hossain博士)及其合作者的职业发展；(2)ACL将采取更全面的方法，为其用户群提供更好的服务；(3)ACL将为主要设备提供讲习班，包括LC/MS/MS、CE/MS/MS、LC-ICP/MS、拉曼显微镜系统、FT-IR以及其他常规仪器，至少每学期一次；(4)ACL计划购买三台新设备以及计算机和打印机，以满足其用户群的需求；(5)acl计划翻新两个实验室空间以容纳新设备，使其运行更有效率，并为其用户提供更安全的环境；(6)acl将扩大分析用户委员会的作用，通过最大限度地利用资源和建立可靠的成本回收系统来提高其服务质量；及(7)acl将使用更有效的成本回收系统，以迈向财政 独立。这份建议书中概述的改进服务和所需的新设备将帮助三个试点项目(Arslan博士、高博士、Hossain博士)以及其他ACL教员用户，包括Campbell、Hamme、Lee、Liu、Ray、Tchikawa、Yu、Venkatraman、Patlolla、Hwang、M.Begonia、G.Begonia、Li和CSET的其他几名教员，进一步提高他们在环境健康方面的研究效率。

In recent years, the Analytical Core Laboratory (ACL) has significantly contributed to the success of the RCMI Program. During the current grant period, the ACL has provided analytical services to 2 pilot project Pis (Drs. Hamme and Liu) and 17 other faculty members as well as a large number of research associates, technicians, and students in the College of Science, Engineering, and Technology (CSET). These ACL users have been very active in publishing peer- reviewed papers (over 110 in last 5 years) and presenting over 200 papers in national or international conferences during the same period. In addition, faculty members using the ACL are currently receiving twenty two (22) research grants. In order to further improve the productivity of these faculty and to meet the biomedical and environmental health research needs of ACL users, the following plans are proposed: (1) ACL will provide laboratory support for 3 new RCMI pilot projects and contribute to career development for their Pis (Drs. Arslan, Gao & Hossain) and collaborators; (2) ACL will implement a more comprehensive approach to provide better services to its user community; (3) ACL will offer workshops for major equipment including LC/MS/MS, CE/MS/MS, LC-ICP/MS, Raman microscopy system, and FT-IR as well as other conventional instruments at least once a semester; (4) ACL plans to acquire three new equipments as well as computers and printers to satisfy the needs of its user community; (5) ACL plans to renovate two lab spaces for accommodating new equipments, making its operation more efficient, and providing a safer environment for its users; (6) ACL will expand the role of the Analytical Users Committee for improving the quality of its service by maximizing resources and establishing a solid system for cost recovery; and (7) ACL will use a more efficient cost recovery system in order to move towards fiscal independence. The improved services as outlined in this proposal and the requested new equipment will help three pilot projects (Drs. Arslan, Gao, Hossain) as well as other ACL faculty users including Drs. Campbell, Hamme, Lee, Liu, Ray, Tachikawa, Yu, Venkatraman, Patlolla, Hwang, M. Begonia, G. Begonia, Li, and several other faculty members in CSET to further improve the productivity of their research in environmental health.